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This Article Full Text (PDF) All Versions of this Article: jas.2008-1212v1 87/6/2038    most recent Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Huang, Y. L. Articles by Liu, B. Search for Related Content PubMed PubMed Citation Articles by Huang, Y. L. Articles by Liu, B.

Relative bioavailabilities of organic zinc sources with different chelation strengths for broilers fed a conventional corn-soybean meal diet

Y. L. Huang^*,, L. Lu^*, S. F. Li^*, X. G. Luo^* and B. Liu^*

^* Mineral Nutrition Research Division, State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100094, P. R. China College of Life Science and Technology, Southwest University for Nationalities, Chengdu 610041, P. R. China

wlysz{at}263.net

Abstract

An experiment was conducted to estimate relative bioavailability (RBV) of Zn in 3 organic zinc sources with different chelation strength (Q_f) compared to ZnSO₄. A total of 1,092, 1-d-old male broiler chicks were assigned randomly to 6 replicate cages (14 chicks per cage) for each of 13 treatments. Dietary treatments included the basal corn-soybean meal diet (27.82 mg Zn/kg DM) supplemented with 0, 30, 60, or 90 mg of added Zn as reagent ZnSO₄, or Zn sources with Q_f of 6.5 (11.93% Zn; Zn AA C), 30.7 (13.27% Zn; Zn Pro B), or 944.0 (18.61% Zn; Zn Pro A )/kg, which are considered as weak, moderate, or strong chelation strength, respectively. Bone Zn, pancreas Zn, pancreas metallothionein (MT) concentration, and pancreas MT mRNA were analyzed at 6, 10, or 14 d of age. The results showed that bone Zn, pancreas Zn, pancreas MT concentration, and pancreas MT mRNA increased linearly (P < 0.001) as dietary Zn concentration increased at all ages. At 6 d of age, pancreas MT mRNA differed (P < 0.001) among dietary Zn sources, and the same tendency was observed at 10 (P = 0.08), or 14 d (P = 0.06) of age. The R² for a linear model was greater on d 6 than either d 10 or 14 for all the response criteria. Based on slope ratios from the multiple linear regression of pancreas MT mRNA concentration on daily intake of dietary Zn, the bioavailability of Zn AA C, Zn Pro B, and Zn Pro A relative to ZnSO₄ (100%) were 100.0, 121.1, and 72.3%, respectively, at 6 d of age. The results indicated that MT mRNA concentration in pancreas was more sensitive in reflecting differences in bioavailability among organic Zn sources than the MT concentration in pancreas or other indices. Moreover, the bioavailability of organic Zn sources was closely related to their chelation strength.

Key Words: bioavailability • chick • gene expression • metallothionein • zinc