J. Anim Sci.
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Published online first on February 13, 2008
J. Anim Sci. 1910. doi:10.2527/jas.2008-0930
© 2008 American Society of Animal Science

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J. Anim Sci., doi: 10.2527/jas.2008-0930
©Copyright, 2008, The American Society of Animal Science


ARTICLE

Animal Trait Ontology (ATO): the importance and usefulness of a unified trait vocabulary for animal species

L. M. Hughes 1, J. Bao 2, Z -L. Hu 1, V. Honavar 2, J. M. Reecy 1*

1 Department of Animal Science, Center for Integrated Animal Genomics, Iowa State University, 2255 Kildee Hall, Ames, Iowa 50010, USA
2 Department of Computer Science, Artificial Intelligence Research Laboratory, Iowa State University, 211 Atanasoff Hall, Ames, Iowa 50011, USA

* To whom correspondence should be addressed. E-mail: jreecy{at}iastate.edu.


   Abstract

Ontologies help to identify and formally define the entities and relationships in specific domains of interest. Bio-ontologies, in particular, play a central role in the annotation, integration, analysis, and interpretation of biological data. Missing from the number of bio-ontologies, is one which includes phenotypic trait information found in livestock species. As a result, the Animal Trait Ontology (ATO) project being carried out under the auspices of the USDA-National Animal Genome Research Program is aimed at the development of a standardized trait ontology for farm animals and software tools to assist the research community in collaborative creation, editing, maintainance, and use of such an ontology. The ATO is currently inclusive of cattle, pig, and chicken species, and will include other livestock species in the future. The ATO will eventually be linked to other species (e.g., human, rat, mouse) so that comparative analysis can be efficiently performed between species.

Key Words: ontology, trait, phenotype, animal, cattle, chicken




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