J. Anim Sci.
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Published online first on April 12, 2007
J. Anim Sci. 1990. doi:10.2527/jas.2006-755
© 2007 American Society of Animal Science

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J. Anim Sci., doi: 10.2527/jas.2006-755
©Copyright, 2007, The American Society of Animal Science


ARTICLE

Heart fatty acid binding protein is upregulated during porcine adipocyte development

B. Li 1, H. N. Zerby 1, K. Lee 1*

1 Department of Animal Sciences, Ohio State University, Columbus, OH 43210

* To whom correspondence should be addressed. E-mail: lee.2626{at}osu.edu.


   Abstract

Heart fatty acid binding protein (H-FABP) has been associated with intramuscular fat content in pigs. In the present study, we showed that expression of H-FABP mRNA in adipose tissue of adult pigs was 8.5% of heart levels and 30% of skeletal muscle levels, and that H-FABP mRNA was more than 10% of adipocyte fatty acid binding protein (A-FABP) mRNA in adipose tissue. Levels of H-FABP mRNA reached a maximum in adipose tissue from 7d neonates with no further increase in the adult. Also, H-FABP mRNA was induced during adipogenic differentiation of stromal-vascular cells derived from both adipose tissue and skeletal muscle. In conclusion, H-FABP may play a role in adipose tissue development and function in the pig.

Key Words: Adipocyte fatty acid binding protein, adipose tissue, heart fatty acid binding protein, skeletal muscle




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