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Journal of Animal Science, Vol 76, Issue 4 1216-1231, Copyright © 1998 by American Society of Animal Science

JOURNAL ARTICLE

Statistical analysis of repeated measures data using SAS procedures

R. C. Littell, P. R. Henry and C. B. Ammerman
Department of Statistics, University of Florida, Gainesville 32611-0339, USA.

Mixed linear models were developed by animal breeders to evaluate genetic potential of bulls. Application of mixed models has recently spread to all areas of research, spurred by availability of advanced computer software. Previously, mixed model analyses were implemented by adapting fixed-effect methods to models with random effects. This imposed limitations on applicability because the covariance structure was not modeled. This is the case with PROC GLM in the SAS System. Recent versions of the SAS System include PROC MIXED. This procedure implements random effects in the statistical model and permits modeling the covariance structure of the data. Thereby, PROC MIXED can compute efficient estimates of fixed effects and valid standard errors of the estimates. Modeling the covariance structure is especially important for analysis of repeated measures data because measurements taken close in time are potentially more highly correlated than those taken far apart in time.


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[Abstract] [Full Text] [PDF]

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 J ANIM SCIHome page
S. A. Bhatti, J. G. P. Bowman, J. L. Firkins, A. V. Grove, and C. W. Hunt
Effect of intake level and alfalfa substitution for grass hay on ruminal kinetics of fiber digestion and particle passage in beef cattle
J Anim Sci, January 1, 2008; 86(1): 134 - 145.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
Y.-H. Chung, D. E. Rico, C. M. Martinez, T. W. Cassidy, V. Noirot, A. Ames, and G. A. Varga
Effects of Feeding Dry Glycerin to Early Postpartum Holstein Dairy Cows on Lactational Performance and Metabolic Profiles
J Dairy Sci, December 1, 2007; 90(12): 5682 - 5691.
[Abstract] [Full Text] [PDF]

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 J ANIM SCIHome page
M. Berkeveld, P. Langendijk, J. E. Bolhuis, A. P. Koets, J. H. M. Verheijden, and M. A. M. Taverne
Intermittent suckling during an extended lactation period: Effects on piglet behavior
J Anim Sci, December 1, 2007; 85(12): 3415 - 3424.
[Abstract] [Full Text] [PDF]

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 J ANIM SCIHome page
J. H. Clark, K. C. Olson, T. B. Schmidt, M. L. Linville, D. O. Alkire, D. L. Meyer, G. K. Rentfrow, C. C. Carr, and E. P. Berg
Effects of dry matter intake restriction on diet digestion, energy partitioning, phosphorus retention, and ruminal fermentation by beef steers
J Anim Sci, December 1, 2007; 85(12): 3383 - 3390.
[Abstract] [Full Text] [PDF]

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 HypertensionHome page
I. Hajjar, D. T. Lackland, L. A. Cupples, and L. A. Lipsitz
Association Between Concurrent and Remote Blood Pressure and Disability in Older Adults
Hypertension, December 1, 2007; 50(6): 1026 - 1032.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
J. P. Goff, E. C. Brummer, S. J. Henning, R. K. Doorenbos, and R. L. Horst
Effect of Application of Ammonium Chloride and Calcium Chloride on Alfalfa Cation-Anion Content and Yield
J Dairy Sci, November 1, 2007; 90(11): 5159 - 5164.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
J. K. Drackley, T. R. Overton, G. Ortiz-Gonzalez, A. D. Beaulieu, D. M. Barbano, J. M. Lynch, and E. G. Perkins
Responses to Increasing Amounts of High-Oleic Sunflower Fatty Acids Infused into the Abomasum of Lactating Dairy Cows
J Dairy Sci, November 1, 2007; 90(11): 5165 - 5175.
[Abstract] [Full Text] [PDF]

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 Biol. Reprod.Home page
A. P Alexenko, J. Mao, M. R Ellersieck, A. M Davis, J. J Whyte, C. S Rosenfeld, and R. M. Roberts
The Contrasting Effects of Ad Libitum and Restricted Feeding of a Diet Very High in Saturated Fats on Sex Ratio and Metabolic Hormones in Mice
Biol Reprod, October 1, 2007; 77(4): 599 - 604.
[Abstract] [Full Text] [PDF]

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 J ANIM SCIHome page
V. Robles, L. A. Gonzalez, A. Ferret, X. Manteca, and S. Calsamiglia
Effects of feeding frequency on intake, ruminal fermentation, and feeding behavior in heifers fed high-concentrate diets
J Anim Sci, October 1, 2007; 85(10): 2538 - 2547.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
S. N. Korosteleva, T. K. Smith, and H. J. Boermans
Effects of Feedborne Fusarium Mycotoxins on the Performance, Metabolism, and Immunity of Dairy Cows
J Dairy Sci, August 1, 2007; 90(8): 3867 - 3873.
[Abstract] [Full Text] [PDF]

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 Proc. Natl. Acad. Sci. USAHome page
C.-Q. Zhu, S. N. Popova, E. R. S. Brown, D. Barsyte-Lovejoy, R. Navab, W. Shih, M. Li, M. Lu, I. Jurisica, L. Z. Penn, et al.
Integrin {alpha}11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells
PNAS, July 10, 2007; 104(28): 11754 - 11759.
[Abstract] [Full Text] [PDF]

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 ReproductionHome page
L F C Brito, A D Barth, N C Rawlings, R E Wilde, D H Crews Jr, Y R Boisclair, R A Ehrhardt, and J P Kastelic
Effect of feed restriction during calfhood on serum concentrations of metabolic hormones, gonadotropins, testosterone, and on sexual development in bulls
Reproduction, July 1, 2007; 134(1): 171 - 181.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
W. Hu, M. R. Murphy, P. D. Constable, and E. Block
Dietary Cation-Anion Difference Effects on Performance and Acid-Base Status of Dairy Cows Postpartum
J Dairy Sci, July 1, 2007; 90(7): 3367 - 3375.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
D. B. Carlson, J. W. McFadden, A. D'Angelo, J. C. Woodworth, and J. K. Drackley
Dietary L-Carnitine Affects Periparturient Nutrient Metabolism and Lactation in Multiparous Cows
J Dairy Sci, July 1, 2007; 90(7): 3422 - 3441.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
J. A. A. Pires, A. H. Souza, and R. R. Grummer
Induction of Hyperlipidemia by Intravenous Infusion of Tallow Emulsion Causes Insulin Resistance in Holstein Cows
J Dairy Sci, June 1, 2007; 90(6): 2735 - 2744.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
D. B. Carlson, J. C. Woodworth, and J. K. Drackley
Effect of L-Carnitine Infusion and Feed Restriction on Carnitine Status in Lactating Holstein Cows
J Dairy Sci, May 1, 2007; 90(5): 2367 - 2376.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
R. F. Cooke, N. S. Del Rio, D. Z. Caraviello, S. J. Bertics, M. H. Ramos, and R. R. Grummer
Supplemental Choline for Prevention and Alleviation of Fatty Liver in Dairy Cattle
J Dairy Sci, May 1, 2007; 90(5): 2413 - 2418.
[Abstract] [Full Text] [PDF]

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 J ANIM SCIHome page
R. Flores, M. L. Looper, R. W. Rorie, M. A. Lamb, S. T. Reiter, D. M. Hallford, D. L. Kreider, and C. F. Rosenkrans Jr.
Influence of body condition and bovine somatotropin on estrous behavior, reproductive performance, and concentrations of serum somatotropin and plasma fatty acids in postpartum Brahman-influenced cows
J Anim Sci, May 1, 2007; 85(5): 1318 - 1329.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
G. R. Oetzel, K. M. Emery, W. P. Kautz, and J. E. Nocek
Direct-Fed Microbial Supplementation and Health and Performance of Pre- and Postpartum Dairy Cattle: A Field Trial
J Dairy Sci, April 1, 2007; 90(4): 2058 - 2068.
[Abstract] [Full Text] [PDF]

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 J. Nutr.Home page
C. L. Kien, R. Blauwiekel, J. Y. Bunn, T. L. Jetton, W. L. Frankel, and J. J. Holst
Cecal Infusion of Butyrate Increases Intestinal Cell Proliferation in Piglets
J. Nutr., April 1, 2007; 137(4): 916 - 922.
[Abstract] [Full Text] [PDF]

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 J. Environ. Qual.Home page
B. R. Ball Coelho, R. C. Roy, E. Topp, and D. R. Lapen
Tile Water Quality following Liquid Swine Manure Application into Standing Corn
J. Environ. Qual., March 1, 2007; 36(2): 580 - 587.
[Abstract] [Full Text] [PDF]

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 J EndocrinolHome page
P. R Buff, N. T Messer IV, A. M Cogswell, D. A Wilson, P. J Johnson, D. H Keisler, and V. K Ganjam
Induction of pulsatile secretion of leptin in horses following thyroidectomy
J. Endocrinol., February 1, 2007; 192(2): 353 - 359.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
G. I. Zanton, M. T. Gabler, and A. J. Heinrichs
Manipulation of Soluble and Rumen-Undegradable Protein in Diets Fed to Postpubertal Dairy Heifers
J Dairy Sci, February 1, 2007; 90(2): 978 - 986.
[Abstract] [Full Text] [PDF]

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 Poult. Sci.Home page
A. Z. Odabasi, R. D. Miles, M. O. Balaban, and K. M. Portier
Changes in Brown Eggshell Color As the Hen Ages
Poult. Sci., February 1, 2007; 86(2): 356 - 363.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
B. Badaoui, J. M. Serradilla, A. Tomas, B. Urrutia, J. L. Ares, J. Carrizosa, A. Sanchez, J. Jordana, and M. Amills
Goat Acetyl-Coenzyme A Carboxylase {alpha}: Molecular Characterization, Polymorphism, and Association with Milk Traits
J Dairy Sci, February 1, 2007; 90(2): 1039 - 1043.
[Abstract] [Full Text] [PDF]

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 J DAIRY SCIHome page
D. B. Carlson, N. B. Litherland, H. M. Dann, J. C. Woodworth, and J. K. Drackley
Metabolic Effects of Abomasal L-Carnitine Infusion and Feed Restriction in Lactating Holstein Cows
J Dairy Sci, December 1, 2006; 89(12): 4819 - 4834.
[Abstract] [Full Text] [PDF]

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 J Med MicrobiolHome page
R. C. Rigden, D. M. Jandhyala, C. Dupont, D. Crosbie-Caird, N. Lopez-Villalobos, N. Maeda, B. Gicquel, and A. Murray
Humoral and cellular immune responses in sheep immunized with a 22 kilodalton exported protein of Mycobacterium avium subspecies paratuberculosis.
J. Med. Microbiol., December 1, 2006; 55(Pt 12): 1735 - 1740.
[Abstract] [Full Text] [PDF]

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 J ANIM SCIHome page
I. Rosenfeld, D. Austbo, and H. Volden
Models for estimating digesta passage kinetics in the gastrointestinal tract of the horse
J Anim Sci, December 1, 2006; 84(12): 3321 - 3328.
[Abstract] [Full Text] [PDF]

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 Am. J. Physiol. Heart Circ. Physiol.Home page
T. A. Quinn, G. Berberian, S. E. Cabreriza, L. J. Maskin, A. D. Weinberg, J. W. Holmes, and H. M. Spotnitz
Effects of sequential biventricular pacing during acute right ventricular pressure overload
Am J Physiol Heart Circ Physiol, November 1, 2006; 291(5): H2380 - H2387.
[Abstract] [Full Text] [PDF]


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