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Requirement of the Baby Pig for Vitamin B₁₂ Fed as a Concentrate

University of Illinois^,2 and Sloan-Kettering Institute for Cancer Research^,3

Abstract

Favorable growth responses were obtained when sufficiently high levels of a vitamin B₁₂ concentrate were added to the basal alpha-protein diet, which is low in vitamin B₁₂.

When 50 micrograms of vitamin B₁₂ per Kg. of dry matter of the diet were fed, optimum growth rates were obtained. The addition of more vitamin B₁₂ concentrate did not result in a further growth response.

Even the highest levels of vitamin B₁₂ concentrate fed did not induce completely normal hematopoiesis in 77 days of observation, as indicated by an abnormally high total erythroid percentage in the bone marrow.

Gross symptoms which might be attributed to the deficiency existing in the basal diet were hyper-irritability, posterior incoordination, voice failure, and pain in the rear quarters.

¹ We are glad to acknowledge the help of Dr. L. E. Boley of the University of Illinois College of Veterinary Medicine for taking the blood samples by heart puncture.

We are grateful for the generous support of Dr. C. P. Rhoads, Director of the Sloan-Kettering Institute for Cancer Research, New York, in making possible the cooperation of Dr. Thiersch in this work.

² Division of Animal Nutrition and Department of Animal Science.

³ New York, N. Y.