J. Anim Sci.
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J. Anim Sci. 2008. 86:2430-2441. doi:10.2527/jas.2008-0921
© 2008 American Society of Animal Science
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SPECIAL TOPICS

CENTENNIAL PAPER: Proteomics in animal science

J. D. Lippolis1 and T. A. Reinhardt

Periparturient Diseases of Cattle Research Unit, USDA-ARS, National Animal Disease Center, Ames, IA 50010

1 Corresponding author: john.lippolis{at}ars.usda.gov

Proteomics holds significant promise as a method for advancing animal science research. The use of this technology in animal science is still in its infancy. The ability of proteomics to simultaneously identify and quantify potentially thousands of proteins is unparalleled. In this review, we will discuss basic principles of doing a proteomic experiment. In addition, challenges and limitations of proteomics will be considered, stressing those that are unique to animal sciences. The current proteomic research in animal sciences will be discussed, and the potential uses for this technology will be highlighted.

Key Words: mass spectrometry • proteomics • protein expression






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