J. Anim Sci.
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J. Anim Sci. 2008. 86:1485-1491. doi:10.2527/jas.2008-0930
© 2008 American Society of Animal Science

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SPECIAL TOPICS

Animal trait ontology: The importance and usefulness of a unified trait vocabulary for animal species

L. M. Hughes*, J. Bao{dagger}, Z.-L. Hu*, V. Honavar{dagger} and J. M. Reecy*

* Department of Animal Science, Center for Integrated Animal Genomics, Iowa State University, 2255 Kildee Hall, Ames 50011; and and {dagger} Department of Computer Science, Artificial Intelligence Research Laboratory, Iowa State University, 211 Atanasoff Hall, Ames 50011

1 Corresponding author: jreecy{at}iastate.edu

Ontologies help to identify and formally define the entities and relationships in specific domains of interest. Bio-ontologies, in particular, play a central role in the annotation, integration, analysis, and interpretation of biological data. Missing from the number of bio-ontologies is one that includes phenotypic trait information found in livestock species. As a result, the Animal Trait Ontology (ATO) project being carried out under the auspices of the USDA-National Animal Genome Research Program is aimed at the development of a standardized trait ontology for farm animals and software tools to assist the research community in collaborative creation, editing, maintenance, and use of such an ontology. The ATO is currently inclusive of cattle, pig, and chicken species, and will include other livestock species in the future. The ATO will eventually be linked to other species (e.g., human, rat, mouse) so that comparative analysis can be efficiently performed between species.

Key Words: ontology • trait • phenotype • animal • cattle • chicken







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