J. Anim Sci.
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J. Anim Sci. 2007. 85:1940-1945. doi:10.2527/jas.2006-836
© 2007 American Society of Animal Science

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ANIMAL GROWTH, PHYSIOLOGY, AND REPRODUCTION

Comparison of progestin-based protocols to synchronize estrus and ovulation before fixed-time artificial insemination in postpartum beef cows1

D. J. Schafer*, J. F. Bader*, J. P. Meyer*, J. K. Haden{dagger}, M. R. Ellersieck{ddagger}, M. C. Lucy*, M. F. Smith* and D. J. Patterson*,2

* Division of Animal Sciences, University of Missouri, Columbia 65211; and {dagger} MFA Inc., Columbia 65202; and {ddagger} Agriculture Experiment Station, University of Missouri, Columbia 65211

2 Corresponding author: pattersond{at}missouri.edu

This experiment was designed to compare pregnancy rates in postpartum beef cows resulting from fixed-time AI (FTAI) after treatment with 1 of 2 protocols to synchronize estrus and ovulation. Cross-bred, suckled beef cows (n = 650) at 4 locations (n = 210; n = 158; n = 88; and n = 194) were assigned within a location to 1 of 2 protocols within age group by days postpartum and BCS. Cows assigned to the melengestrol acetate (MGA) Select treatment (MGA Select; n = 327) were fed MGA (0.5 mg·head–1·d–1) for 14 d, GnRH (100 µg of Cystorelin i.m.) was injected on d 26, and prostaglandin F2{alpha} (PG; 25 mg of Lutalyse i.m.) was injected on d 33. Cows assigned to the CO-Synch + controlled internal drug release (CIDR) protocol (CO-Synch + CIDR; n = 323) were fed a carrier for 14 d, were injected with GnRH and equipped with an EAZI-BREED CIDR insert (1.38 g of progesterone, Pfizer Animal Health, New York, NY) 12 d after carrier removal, and PG (25 mg of Lutalyse i.m.) was injected and the CIDR were removed on d 33. Fixed-time AI was performed at 72 or 66 h after PG for the MGA Select or CO-Synch + CIDR groups, respectively. All cows were injected with GnRH (100 µg of Cystorelin i.m.) at the time of insemination. Blood samples were collected 8 and 1 d before the beginning of MGA or carrier to determine estrous cyclicity status of the cows (estrous cycling vs. anestrus) before treatment [progesterone ≥ 0.5 ng/mL (MGA Select, 185/327, 57%; CO-Synch + CIDR, 177/323, 55%); P = 0.65]. There was no difference (P = 0.20) in pregnancy rate to FTAI between treatments (MGA Select, 201/327, 61%; CO-Synch + CIDR, 214/323, 66%). There was also no difference (P = 0.25) between treatments in final pregnancy rate at the end of the breeding period (MGA Select, 305/327, 93%; CO-Synch + CIDR, 308/323, 95%). These data indicate that pregnancy rates to FTAI were comparable after administration of the MGA Select or CO-Synch + CIDR protocols. Both protocols provide opportunities for beef producers to utilize AI and potentially eliminate the need to detect estrus.

Key Words: beef cow • controlled internal drug release insert • estrus synchronization • fixed-time artificial insemination • melengestrol acetate • progestin




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