HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Sanchez, M.-P. Articles by Milan, D. Search for Related Content PubMed PubMed Citation Articles by Sanchez, M.-P. Articles by Milan, D.

Effects of quantitative trait loci on chromosomes 1, 2, 4, and 7 on growth, carcass, and meat quality traits in backcross Meishan x Large White pigs¹

M.-P. Sanchez^*,2, J. Riquet, N. Iannuccelli, J. Gogué, Y. Billon, O. Demeure, J.-C. Caritez, G. Burgaud, K. Fève, M. Bonnet, C. Péry, H. Lagant^*, P. Le Roy^*, J.-P. Bidanel^* and D. Milan

^* Station de Génétique Quantitative et Appliquée, INRA, 78352 Jouy-en-Josas Cedex, France; and Laboratoire de Génétique Cellulaire, INRA, 31326 Castanet-Tolosan Cedex, France; and Domaine expérimental de Galle, INRA, 18520 Avord, France; and and Domaine expérimental du Magneraud, INRA, 17700 Surgères, France

² Corresponding author: marie-pierre.sanchez{at}jouy.inra.fr

The aim of this work was to estimate whether genetic dissection of QTL on chromosomes 1, 2, 4, and 7, detected in an F₂ Meishan x Large White population, can be achieved with a recombinant back-cross progeny test approach. For this purpose, a first generation of backcross (BC₁) was produced by using frozen semen of F₁ Large White x Meishan boars with Large White females. Four BC₁ boars were selected because of their heterozygosity for at least 1 of the 4 regions. The BC₁ boars were crossed with Large White sows, and the resulting BC₂ offspring were measured for several growth and body composition traits. Contrary to the F₂ animals, BC₂ animals were also measured for meat quality traits in adductor, gluteus superficialis (GS), longissimus dorsi, and biceps femoris (BF) muscles. Each BC₁ boar was tested for a total of 39 traits and for the 4 regions with statistical interval mapping analyses. The QTL effects obtained in BC₁ families showed some differences compared with those described in F₁ families. However, we confirmed QTL effects for growth in the SW1301–SW2512 markers interval on chromosome 1 and also for body composition in the SW1828–SW2512 markers interval on chromosome 1, in the SW2443–SWR783 markers interval on chromosome 2, and in the SW1369–SW632 markers interval on chromosome 7. In addition, we detected new QTL for growth traits on chromosome 2 and for meat quality traits on chromosomes 1 and 2. Growth of animals from weaning to the end of the test was influenced by the IGF2 gene region on chromosome 2. Concerning meat quality, ultimate pH of adductor, longissimus dorsi, and BF were affected by the interval delimited by UMNP3000 and SW2512 markers on chromosome 1, and a* of GS, L* of BF, and water-holding capacity of GS were affected by QTL located between marker loci SW2443 and SWR783 on chromosome 2. Recombinant progeny testing appeared to be a suitable strategy for the genetic dissection of the QTL investigated.

Key Words: backcross • body composition • growth • meat quality • pig • quantitative trait loci

This article has been cited by other articles:

				J. Demars, J. Riquet, M.-P. Sanchez, Y. Billon, J.-F. Hocquette, B. Lebret, N. Iannuccelli, J.-P. Bidanel, D. Milan, and F. Gondret Metabolic and histochemical characteristics of fat and muscle tissues in homozygous or heterozygous pigs for the body composition QTL located on chromosome 7 Physiol Genomics, August 20, 2007; 30(3): 232 - 241. [Abstract] [Full Text] [PDF]