HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Nofrarías, M. Articles by Gasa, J. Search for Related Content PubMed PubMed Citation Articles by Nofrarías, M. Articles by Gasa, J.

Effects of spray-dried porcine plasma and plant extracts on intestinal morphology and on leukocyte cell subsets of weaned pigs¹

M. Nofrarías^*,2, E. G. Manzanilla, J. Pujols, X. Gibert, N. Majó^*, J. Segalés^* and J. Gasa

^* Centre de Recerca en Sanitat Animal (CReSA)—Departament de Sanitat i d’Anatomia Animals, Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain; and Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain; and CReSA—Institut de Recerca i Tecnologia Agroalimentaria (IRTA), 08007, Barcelona, Spain

² Correspondence: miquel.nofrarias{at}cresa.uab.es

We evaluated the effects of a 6% spray-dried porcine plasma (SDPP) and a plant extracts mixture (XT; 5% carvacrol, 3% cinnamaldehyde, and 2% capsicum oleoresin) on the productive performance, intestinal morphology, and leukocyte cell subsets of early-weaned pigs compared with a control group. Morphometry of the jejunum, ileum, and colon, and immune cell analysis of blood, ileocolic lymph node (LN), and ileal Peyer’s patches were done in 24 weaned pigs (20 ± 2 d) at 19 or 21 d postweaning. Although SDPP and XT treatments did not increase ADG or ADFI, SDPP improved the G:F ratio (P = 0.024) compared with the control group. Dietary SDPP reduced the percentages of blood monocytes (P = 0.006) and macrophages in ileal Peyer’s patches and LN (P = 0.04), of B lymphocytes (P = 0.04) and + T cells in LN (P = 0.009), and of intraepithelial lymphocytes (P = 0.026) as well as the density of lamina propria cells in the colon (P < 0.01). Dietary XT reduced intraepithelial lymphocyte numbers in jejunum (P = 0.034) and the percentages of blood cytotoxic cells (P = 0.07) and B lymphocytes in LN (P = 0.03); however, XT increased blood monocytes (P = 0.038) and the density of lamina propria lymphocytes in the colon (P = 0.003). These results indicate that dietary SDPP and plant extracts can affect intestinal morphology and immune cell subsets of gut tissues and blood in weaned pigs. Furthermore, the effects of SDPP suggest lower activation of the immune system of the piglets.

Key Words: immunology • intestinal morphology • plant extract • spray-dried plasma • weaning pig

This article has been cited by other articles:

				W. Windisch, K. Schedle, C. Plitzner, and A. Kroismayr Use of phytogenic products as feed additives for swine and poultry J Anim Sci, April 1, 2008; 86(14_suppl): E140 - E148. [Abstract] [Full Text] [PDF]

				A. Perez-Bosque, L. Miro, J. Polo, L. Russell, J. Campbell, E. Weaver, J. Crenshaw, and M. Moreto Dietary Plasma Proteins Modulate the Immune Response of Diffuse Gut-Associated Lymphoid Tissue in Rats Challenged with Staphylococcus aureus Enterotoxin B J. Nutr., March 1, 2008; 138(3): 533 - 537. [Abstract] [Full Text] [PDF]

				J. D. Crenshaw, R. D. Boyd, J. M. Campbell, L. E. Russell, R. L. Moser, and M. E. Wilson Lactation feed disappearance and weaning to estrus interval for sows fed spray-dried plasma J Anim Sci, December 1, 2007; 85(12): 3442 - 3453. [Abstract] [Full Text] [PDF]