| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
ANIMAL GENETICS |
* Genome Research Department, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305-0901, Japan;
and
Livestock Research Institute, Tokushima Agriculture, Forestry and Fisheries Technology Center, Anan, Tokushima 774-0047, Japan; and
and
STAFF Institute, Tsukuba, Ibaraki 305-0854, Japan
2 Correspondence: Ikenodai 2 (phone: 81-29-838-8627; fax: 81-29-838-8627; e-mail: mikawa{at}affrc.go.jp).
The objective of the research was to identify QTL affecting the number of vertebrae in swine, one of the major determining factors of growth and body composition. Previously, we reported a QTL for the number of vertebrae located on SSC1qter (terminal band of the q arm of SSC 1) in an F2 family produced by crossing a Göttingen miniature male with two Meishan females. Eight other swine families were subsequently produced by crosses between different breeds of European, Asian, and miniature pigs. In these families, the QTL on SSC1qter for the number of vertebrae was detected. Unlike the Asian alleles, all European alleles in this study had the effect of increasing the number of vertebrae by 0.44 to 0.69 and acted additively without dominance. The Göttingen miniature sire, for which we previously reported a smaller additive effect, seemed to be heterozygous at the QTL. In the present study, another QTL was found for the number of vertebrae on SSC7. This QTL was not fixed in the European pigs used as parents in our experimental families, and some of the European alleles increased the number of vertebrae. A half-sib analysis confirmed that this QTL was segregating in a commercial Large White population. Analysis in an F2 family in which the parental pigs were fixed for alternative alleles revealed that the effects of the QTL on SSC1 and on SSC7 were additive and similar in size. The two QTL acted independently without epistatic effects and explained an increase of more than two vertebrae.
Key Words: Pigs • Quantitative Trait Loci • Swine • Vertebrae
This article has been cited by other articles:
|
|
 |
|
  D. B. Edwards, C. W. Ernst, N. E. Raney, M. E. Doumit, M. D. Hoge, and R. O. Bates Quantitative trait locus mapping in an F2 Duroc x Pietrain resource population: II. Carcass and meat quality traits J Anim Sci, February 1, 2008; 86(2): 254 - 266. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Mikawa, T. Morozumi, S.-I. Shimanuki, T. Hayashi, H. Uenishi, M. Domukai, N. Okumura, and T. Awata Fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (NR6A1) Genome Res., May 1, 2007; 17(5): 586 - 593. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
