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Bioefficacy of L-lysine sulfate compared with feed-grade L-lysine•HCl in young pigs

M. R. Smiricky-Tjardes^*, I. Mavromichalis^*,1, D. M. Albin^*, J. E. Wubben^*, M. Rademacher^,2 and V. M. Gabert^*,3

^* University of Illinois, Urbana 61801; and and Degussa AG, Hanau-Wolfgang, Germany

² Correspondence: Feed Additives Division, Rodenbacher, Chausee 4, Hanau-Wolfgang, Germany (phone: +49-6181-59-3584; fax: +49-6181-59-2129; e-mail: meike.rademacher{at}degussa.com).

A pig growth assay was conducted to determine the relative biological value (RBV) of lysine from L-lysine sulfate compared with feed-grade L-lysine•HCl. One hundred nursery pigs with an average initial BW of 9.5 ± 1.5 kg were blocked by BW and gender and allotted randomly to five dietary treatments in five replicates of four pigs per pen. A corn-peanut meal diet containing 0.6% total lysine (as-fed basis) was supplemented with two levels (0.1 and 0.2%) of lysine from L-lysine•HCl or L-lysine sulfate. The RBV of L-lysine sulfate was determined using multiple regression slope-ratio methodology, with ADG and G:F as the response criteria. At the tested levels, linear responses for gain and G:F were obtained from increments of lysine from the two lysine sources. When ADG was regressed on supplemental lysine intake, the RBV of lysine in L-lysine sulfate was 99% of the RBV of lysine in L-lysine•HCl. When G:F was regressed on supplemental lysine intake, the RBV of lysine in L-lysine sulfate was 97% of the RBV of lysine in L-lysine•HCl. The t-test analysis revealed that the RBV of lysine in L-lysine sulfate was not significantly different from the RBV of lysine in L-lysine•HCl, which was assumed to be 100% bioavailable. In conclusion, L-lysine sulfate can replace L-lysine•HCl in diets for growing swine.

Key Words: L-Lysine•HCl • L-Lysine Sulfate • Pigs • Relative Bioavailability

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