| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
* Department of Animal Science, Texas A&M University, College Station 77843 and
and
Department of Genetics, Faculty of Veterinary Medicine, University of Liège (B43), 4000-Liège, Belgium
2 Correspondence—phone: 515-294-2721; fax: 515-294-9150; E-mail: kimjj{at}iastate.edu.
This study was conducted to detect quantitative trait loci (QTL) affecting growth and beef carcass fatness traits in an experimental population of Angus and Brahman crossbreds. The three-generation mapping population was generated with 602 progeny from 29 reciprocal backcross and three F2 full-sib families, and 417 genetic markers were used to produce a sex-averaged map of the 29 autosomes spanning 2,642.5 Kosambi cM. Alternative interval-mapping approaches were applied under line-cross (LC) and random infinite alleles (RA) models to detect QTL segregating between and within breeds. A total of 35 QTL (five with genomewide significant and 30 with suggestive evidence for linkage) were found on 19 chromosomes. One QTL affecting yearling weight was found with genomewide significant evidence for linkage in the interstitial region of bovine autosome (BTA) 1, and an additional 19 QTL were detected with suggestive evidence for linkage under the LC model. Many of these QTL had a dominant (complete or overdominant) mode of gene action, and only a few of the QTL were primarily additive, which reflects the fact that heterosis for growth is known to be appreciable in crosses among Brahman and British breeds. Four QTL affecting growth were detected with genomewide significant evidence for linkage under the RA model on BTA 2 and BTA 6 for birth weight, BTA 5 for yearling weight, and BTA 23 for hot carcass weight. An additional 11 QTL were detected with suggestive evidence for linkage under the RA model. None of the QTL (except for yearling weight on BTA 5) detected under the RA model were found by the LC analyses, suggesting the segregation of alternate alleles within one or both of the parental breeds. Our results reveal the utility of implementing both the LC and RA models to detect dominant QTL and also QTL with similar allele frequency distributions within parental breeds.
Key Words: Beef Cattle • Carcass Composition • Growth • Mapping • Quantitative Trait Loci
This article has been cited by other articles:
|
|
 |
|
  B. Gutierrez-Gil, J. L. Williams, D. Homer, D. Burton, C. S. Haley, and P. Wiener Search for quantitative trait loci affecting growth and carcass traits in a cross population of beef and dairy cattle J Anim Sci, January 1, 2009; 87(1): 24 - 36. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Garrett, G. Rincon, J. F. Medrano, M. A. Elzo, G. A. Silver, and M. G. Thomas Promoter region of the bovine growth hormone receptor gene: Single nucleotide polymorphism discovery in cattle and association with performance in Brangus bulls J Anim Sci, December 1, 2008; 86(12): 3315 - 3323. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Abe, J. Saburi, H. Hasebe, T. Nakagawa, T. Kawamura, K. Saito, T. Nade, S. Misumi, T. Okumura, K. Kuchida, et al. Bovine quantitative trait loci analysis for growth, carcass, and meat quality traits in an F2 population from a cross between Japanese Black and Limousin J Anim Sci, November 1, 2008; 86(11): 2821 - 2832. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Nkrumah, E. L. Sherman, C. Li, E. Marques, D. H. Crews Jr., R. Bartusiak, B. Murdoch, Z. Wang, J. A. Basarab, and S. S. Moore Primary genome scan to identify putative quantitative trait loci for feedlot growth rate, feed intake, and feed efficiency of beef cattle J Anim Sci, December 1, 2007; 85(12): 3170 - 3181. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. M. Sellner, J. W. Kim, M. C. McClure, K. H. Taylor, R. D. Schnabel, and J. F. Taylor BOARD-INVITED REVIEW: Applications of genomic information in livestock J Anim Sci, December 1, 2007; 85(12): 3148 - 3158. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. K. Musani, N. D. Halbert, D. T. Redden, D. B. Allison, and J. N. Derr Marker Genotypes and Population Admixture and Their Association With Body Weight, Height and Relative Body Mass in United States Federal Bison Herds Genetics, October 1, 2006; 174(2): 775 - 783. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Kneeland, C. Li, J. Basarab, W. M. Snelling, B. Benkel, B. Murdoch, C. Hansen, and S. S. Moore Identification and fine mapping of quantitative trait loci for growth traits on bovine chromosomes 2, 6, 14, 19, 21, and 23 within one commercial line of Bos taurus J Anim Sci, December 1, 2004; 82(12): 3405 - 3414. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Mizoshita, T. Watanabe, H. Hayashi, C. Kubota, H. Yamakuchi, J. Todoroki, and Y. Sugimoto Quantitative trait loci analysis for growth and carcass traits in a half-sib family of purebred Japanese Black (Wagyu) cattle J Anim Sci, December 1, 2004; 82(12): 3415 - 3420. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Casas, S. D. Shackelford, J. W. Keele, M. Koohmaraie, T. P. L. Smith, and R. T. Stone Detection of quantitative trait loci for growth and carcass composition in cattle J Anim Sci, December 1, 2003; 81(12): 2976 - 2983. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
