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Effect of Tryptophan Deficiency on the Pig¹

Purdue University Agricultural Experiment Station

Abstract

Tryptophan has been proven indispensable for growing Duroc weanling pigs by the use of a purified diet which was deficient in this amino acid.

Lack of tryptophan decreases the feed efficiency and feed consumption, and causes a loss in weight in young pigs.

Although the minimum level of tryptophan needed for optimum growth and feed efficiency is not known, a level of 0.4% of DL-tryptophan seems to be adequate to meet the normal requirement in pigs weighing 50 to 100 lbs.

A purified diet has been formulated which supports a rate of growth equal to that obtained on a good natural grain ration.

¹ Contribution from the Departments of Animal Husbandry and Agricultural Chemistry, Journal paper No. 387 Purdue University, Agricultural Experiment Station, Lafayette, Indiana.

² The authors are grateful to Eli Lilly and Co., Indianapolis, Indiana for the hydrolyzed fish protein and liver extract used in this study, and to A. Lee Caldwell and George Schnakenberg of the Lilly Research Laboratories for the preparation of the tryptophan-free hydrolyzed fish protein.