J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zhao, F. Q.
Right arrow Articles by Kennelly, J. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zhao, F. Q.
Right arrow Articles by Kennelly, J. J.

Journal of Animal Science, Vol 77, Issue 9 2517-2522, Copyright © 1999 by American Society of Animal Science

JOURNAL ARTICLE

Glucose transporter gene expression in bovine mammary gland

F. Q. Zhao, E. K. Okine and J. J. Kennelly
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada.

Transport of glucose across the plasma membrane of mammary epithelial cells is believed to be a passive process of facilitated diffusion mediated by facilitative glucose transporter(s). This article presents three lines of evidence that indicate the expression of sodium/glucose cotransporter (SGLT1) in the mammary gland of lactating and nonlactating cows. First, transcripts of SGLT1 mRNA ranging in size from 1.5 to 5.2 kb were detected in polyadenylated RNA preparations of mammary glands of lactating and nonlactating cows. Second, SGLT1 cotransporter protein was also detected in plasma membrane preparations of mammary glands of lactating cows. Third, partial amino acid sequence deduced from the reverse transcriptase-PCR fragment of SGLT1 from bovine mammary glands was similar to the sequence reported for ovine SGLT1. We conclude that mammary gland expression of SGLT1 mRNA and protein suggests that an active glucose transport system may be involved in glucose transport and metabolism in the mammary gland of dairy cows. However, the physiological significance of the expression of SGLT1 in mammary gland remains unknown.


This article has been cited by other articles:


Home page
 J DAIRY SCIHome page
F.-Q. Zhao and A. F. Keating
Expression and Regulation of Glucose Transporters in the Bovine Mammary Gland
J Dairy Sci, June 1, 2007; 90(13_suppl): E76 - E86.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
C. T. Xiao and J. P. Cant
Relationship Between Glucose Transport and Metabolism in Isolated Bovine Mammary Epithelial Cells
J Dairy Sci, August 1, 2005; 88(8): 2794 - 2805.
[Abstract] [Full Text] [PDF]

Home page
 J ANIM SCIHome page
T. Komatsu, F. Itoh, S. Kushibiki, and K. Hodate
Changes in gene expression of glucose transporters in lactating and nonlactating cows
J Anim Sci, March 1, 2005; 83(3): 557 - 564.
[Abstract] [Full Text] [PDF]

Home page
 J DAIRY SCIHome page
F.-Q. Zhao, Y.-C. Zheng, E. H. Wall, and T. B. McFadden
Cloning and Expression of Bovine Sodium/Glucose Cotransporters
J Dairy Sci, January 1, 2005; 88(1): 182 - 194.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1999 by the American Society of Animal Science.