J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hathaway, M. R.
Right arrow Articles by Doan, T. N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hathaway, M. R.
Right arrow Articles by Doan, T. N.

Journal of Animal Science, Vol 77, Issue 12 3208-3214, Copyright © 1999 by American Society of Animal Science

JOURNAL ARTICLE

Effect of feed intake on antimicrobially induced increases in porcine serum insulin-like growth factor I

M. R. Hathaway, W. R. Dayton, M. E. White, T. L. Henderson, D. A. Young and T. N. Doan
Department of Animal Science, University of Minnesota, St. Paul 55108, USA. hathaway@tc.umn.edu

This study was conducted to determine whether an antimicrobially induced (ASP-250) increase in serum IGF-I was the result of differences in feed intake. Serum IGF-I concentrations were measured in crossbred pigs that were fed a control diet or a diet supplemented with ASP-250 either for ad libitum consumption or limited to 85% of the control pigs' consumption. The pigs that consumed either diet ad libitum, control or ASP-250, consumed similar quantities of feed. The ASP-250 ad libitum-intake pigs had serum IGF-I concentrations that were greater (P<.01) than those of their ad libitum-intake control littermates. Similarly, the ASP-250 limit-fed pigs had serum IGF-I concentrations that were greater (P<.01) than those of the controls. Although the serum IGF-I concentrations of pigs fed the ASP-250-supplemented diet for ad libitum intake were greater than the serum IGF-I concentrations of the pigs limit-fed the ASP-250-supplemented diet, the differences were not significant (P<.08). The ASP-250-fed pigs had higher serum IGF binding protein (BP)-3 concentrations than did their control littermates (P<.003). A time course of antimicrobially induced alterations in serum IGF-I concentrations revealed that the effect of increased serum IGF-I levels in ASP-250-supplemented pigs (P<.02) was observed within 4 d and was maintained throughout the 4-wk study. These findings show that feed intake is not responsible for the increase in serum IGF-I observed with ASP-250 supplementation. Additionally, the antimicrobially induced increase in serum IGF-I concentrations occurs within a few days after initiation of the treatment.


This article has been cited by other articles:


Home page
 J ANIM SCIHome page
T. E. Weber and B. J. Kerr
Effect of sodium butyrate on growth performance and response to lipopolysaccharide in weanling pigs
J Anim Sci, February 1, 2008; 86(2): 442 - 450.
[Abstract] [Full Text] [PDF]

Home page
 J ANIM SCIHome page
E. G. Manzanilla, M. Nofrarias, M. Anguita, M. Castillo, J. F. Perez, S. M. Martin-Orue, C. Kamel, and J. Gasa
Effects of butyrate, avilamycin, and a plant extract combination on the intestinal equilibrium of early-weaned pigs
J Anim Sci, October 1, 2006; 84(10): 2743 - 2751.
[Abstract] [Full Text] [PDF]

Home page
 J ANIM SCIHome page
M. R. Hathaway, W. R. Dayton, M. E. White, and M. S. Pampusch
Effects of antimicrobials and weaning on porcine serum insulin-like growth factor binding protein levels
J Anim Sci, June 1, 2003; 81(6): 1456 - 1463.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1999 by the American Society of Animal Science.