| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Journal of Animal Science, Vol 77, Issue 12 3191-3200, Copyright © 1999 by American Society of Animal Science
JOURNAL ARTICLE |
M. Tang, B. Laarveld, A. G. Van Kessel, D. L. Hamilton, A. Estrada and J. F. Patience
Animal Biotechnology Center, Department of Animal & Poultry Science, University of Saskatchewan, Saskatoon, SK, Canada.
The effect of segregated early weaning (SEW) on postweaning small intestinal development was investigated in SEW and control (CON) pigs. Small intestines were collected from a total of 15 pigs killed at 11 (preweaning), 15 (3 d postweaning), and 34 d of age. At 3 d postweaning, the SEW and CON pigs had shorter villi (P<.01), deeper crypts (P<.01), and reduced (P<.01) ratios of villus height:crypt depth (V:C) compared with preweaning. Weaning also reduced specific activities of lactase (P<.01) in duodenum and ileum and alkaline phosphatase (ALP) (P<.05) in duodenum and jejunum. Sucrase activity in the three regions of the small intestine marginally decreased in both groups at 3 d postweaning. The mucosal protein:DNA ratio in duodenum and jejunum increased (P<.05) in SEW and CON pigs at 3 d postweaning compared with preweaning pigs. The SEW and CON treatments resulted in differences in postweaning gut development. At 15 d of age in SEW pigs, the mucosal protein:DNA ratio in duodenum and jejunum were 20 and 25.5% (P<.05) less, respectively, than those in CON pigs. However, at 34 d, these ratios in duodenum, jejunum, and ileum were 43.5 (P<.05), 24.3, and 32.9% (P<.05) greater, respectively, in SEW pigs than in CON pigs. Longer villi, shorter crypts (P<.01), and higher V:C ratios (P<.01) in jejunum and ileum were observed in SEW pigs vs CON pigs at 34 d of age. The specific activities of lactase in duodenum (P<.01) and jejunum (P<.05) and of ALP in duodenum (P<.01) were higher in SEW pigs. Sucrase activity in duodenum, jejunum, and ileum was 21.7, 46.3 (P<.05), and 11.2% greater in SEW pigs at 34 d of age. These results demonstrate differences in postweaning gut development between SEW and CON pigs. Furthermore, the number of intraepithelial lymphocytes in jejunum was greater (P<.001) in 34-d-old SEW pigs compared with CON pigs. Microscopy revealed a thick mucus coating over epithelial cells in the ileum of 34-d-old CON pigs that was not apparent in the SEW pigs. These observations are consistent with reduced pathogen exposure associated with SEW. We suggest that segregated early weaning advances postweaning gut maturation, which is consistent with improved growth and feed efficiency observed in SEW pigs.
This article has been cited by other articles:
|
|
 |
|
  Z. Y. Jiang, L. H. Sun, Y. C. Lin, X. Y. Ma, C. T. Zheng, G. L. Zhou, F. Chen, and S. T. Zou Effects of dietary glycyl-glutamine on growth performance, small intestinal integrity, and immune responses of weaning piglets challenged with lipopolysaccharide J Anim Sci, December 1, 2009; 87(12): 4050 - 4056. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. B. Shen, X. S. Piao, S. W. Kim, L. Wang, P. Liu, I. Yoon, and Y. G. Zhen Effects of yeast culture supplementation on growth performance, intestinal health, and immune response of nursery pigs J Anim Sci, August 1, 2009; 87(8): 2614 - 2624. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Piva, E. Grilli, L. Fabbri, V. Pizzamiglio, P. P. Gatta, F. Galvano, M. Bognanno, L. Fiorentini, J. Wolinski, R. Zabielski, et al. Intestinal metabolism of weaned piglets fed a typical United States or European diet with or without supplementation of tributyrin and lactitol J Anim Sci, November 1, 2008; 86(11): 2952 - 2961. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. Zhan, D. Ou, X. Piao, S. W. Kim, Y. Liu, and J. Wang Dietary Arginine Supplementation Affects Microvascular Development in the Small Intestine of Early-Weaned Pigs J. Nutr., July 1, 2008; 138(7): 1304 - 1309. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. S. Gomez-Conde, J. Garcia, S. Chamorro, P. Eiras, P. G. Rebollar, A. Perez de Rozas, I. Badiola, C. de Blas, and R. Carabano Neutral detergent-soluble fiber improves gut barrier function in twenty-five-day-old weaned rabbits J Anim Sci, December 1, 2007; 85(12): 3313 - 3321. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Lanthier, Y. Lou, M. A. Terner, and E. J. Squires Characterizing developmental changes in plasma and tissue skatole concentrations in the prepubescent intact male pig J Anim Sci, July 1, 2006; 84(7): 1699 - 1708. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Beaulieu, C. L. Levesque, and J. F. Patience The effects of dietary energy concentration and weaning site on weanling pig performance J Anim Sci, May 1, 2006; 84(5): 1159 - 1168. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. C. Brown, C. V. Maxwell, G. F. Erf, M. E. Davis, S. Singh, and Z. B. Johnson Ontogeny of T lymphocytes and intestinal morphological characteristics in neonatal pigs at different ages in the postnatal period J Anim Sci, March 1, 2006; 84(3): 567 - 578. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. C. Ontsouka, B. Korczak, H. M. Hammon, and J. W. Blum Real-Time PCR Quantification of Bovine Lactase mRNA: Localization in the Gastrointestinal Tract of Milk-Fed Calves J Dairy Sci, December 1, 2004; 87(12): 4230 - 4237. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
