Journal of Animal Science, Vol 73, Issue 12 3666-3672, Copyright © 1995 by American Society of Animal Science

CLINICAL TRIAL

The effect of dietary methionine and its relationship to lysine on growth performance of the segregated early-weaned pig

K. Q. Owen, R. D. Goodband, J. L. Nelssen, M. D. Tokach and S. S. Dritz
Department of Animal Sciences and Industry, Kansas State University, Manhattan 66506-0201, USA.

Two experiments were conducted to determine the dietary methionine requirement and the appropriate methionine:lysine for the segregated early weaned-weaned pig. In Exp. 1, 435 crossbred pigs (9.5 +/- 4 d of age and 3.5 kg BW) were fed diets (1.8% lysine, .62% cystine) containing 10% spray-dried plasma protein (SDPP) and 1.75% spray-dried blood meal (SDBM) from day 0 to 21 postweaning. Pigs were feed one of six dietary treatments from .36% to .56% total dietary methionine (.317 to .517% apparent digestible methionine). From d 0 to 7 and d 0 to 21 postweaning, ADG and gain:feed ratio (G/F) increased (linear, P < .01, P < .05, respectively) as dietary methionine increased. In Exp. 2, 350 crossbred pigs (9.0 +/- 2 d of age and 3.8 kg BW) were used to determine the appropriate methionine:lysine ratio for the segregated early-weaned pig in a 2 x 5 factorial arrangement. Two lysine levels (1.8 and 1.4%) and five methionine levels within each lysine level were used to obtain methionine:lysine ratios ranging from 21.5 to 33.5%. From d 0 to 21 postweaning, pigs were assigned to one of 10 dietary treatments containing 25% dried whey, 12% lactose, 7.5% SDPP, 6.0% select menhaden fish meal, and 1.75% SDBM. No methionine x lysine interactions were observed (P > .10). From d 0 to 7 postweaning, increasing dietary methionine improved (quadratic, P < .01) ADG and ADFI regardless of dietary lysine. From d 0 to 14 postweaning, increasing dietary methionine improved ADG (quadratic, P < .01), ADFI quadratic, P =.02), and G/F (quadratic, P < .10). Inflection point analysis projected maximum ADG at methionine:lysine ratios of 27 and 27.5% for pigs fed 1.4 and 1.8% lysine, respectively. Cumulative (d 0 to 21 postweaning) ADG, ADFI, and G/F were improved (quadratic, P < .05) by increasing dietary methionine. Increasing dietary lysine improved (P < .01) ADG and G/F from d 0 to 7, from d 0 to 14, and for the overall experiment. In conclusion, a diet with 1.8% total lysine that includes spray-dried blood products must contain .48 to .52% total dietary methionine (.437 to .477% apparent digestible) or 27.5% of total lysine to maximize growth performance of pigs from d 0 to 21 postweaning (3.5 to 12 kg BW).

This article has been cited by other articles:

				S. Moehn, A. K. Shoveller, M. Rademacher, and R. O. Ball An estimate of the methionine requirement and its variability in growing pigs using the indicator amino acid oxidation technique J Anim Sci, February 1, 2008; 86(2): 364 - 369. [Abstract] [Full Text] [PDF]

				G. F. Yi, A. M. Gaines, B. W. Ratliff, P. Srichana, G. L. Allee, K. R. Perryman, and C. D. Knight Estimation of the true ileal digestible lysine and sulfur amino acid requirement and comparison of the bioefficacy of 2-hydroxy-4-(methylthio)butanoic acid and DL-methionine in eleven- to twenty-six-kilogram nursery pigs J Anim Sci, July 1, 2006; 84(7): 1709 - 1721. [Abstract] [Full Text] [PDF]

				A. M. Gaines, G. F. Yi, B. W. Ratliff, P. Srichana, D. C. Kendall, G. L. Allee, C. D. Knight, and K. R. Perryman Estimation of the ideal ratio of true ileal digestible sulfur amino acids:lysine in 8- to 26-kg nursery pigs J Anim Sci, November 1, 2005; 83(11): 2527 - 2534. [Abstract] [Full Text] [PDF]