J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Adeola, O.
Right arrow Articles by O'Brien, P. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Adeola, O.
Right arrow Articles by O'Brien, P. J.

Journal of Animal Science, Vol 71, Issue 4 968-974, Copyright © 1993 by American Society of Animal Science

JOURNAL ARTICLE

Regional brain neurotransmitter concentrations in stress-susceptible pigs

O. Adeola, R. O. Ball, J. D. House and P. J. O'Brien
Department of Animal Sciences, Purdue University, West Lafayette, IN 47907.

In three experiments, the concentrations of indoleamines and catecholamines were measured in the brain regions of pigs that were homozygous-positive (nn, stress-susceptible), heterozygous (Nn), and homozygous-negative (NN, stress-tolerant) for the halothane gene. In Exp. 1 (n = 10), hypothalamic 5-hydroxytryptophan (P < .1) and serotonin (P < .05) were lower in nn than in NN pigs. Concentrations of 5-hydroxytryptophan, serotonin, dihydroxyphenylethylamine (DOPAMINE), norepinephrine, and epinephrine in the hypothalamus and caudate nucleus were lower (P < .05) in nn (n = 8) than in NN (n = 7) pigs in Exp. 2. However, there were no differences in dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) between nn and NN pigs. Hippocampal serotonin and norepinephrine were lower (P < .05) in nn than in NN pigs. In the third experiment, serotonin was the only neurotransmitter that was lower in the hippocampus of Nn (n = 5) than of NN (n = 6) pigs; concentrations of all other neurotransmitters in the three brain regions were similar between Nn and NN pigs. Results from these experiments suggest central nervous system involvement in porcine stress syndrome.


This article has been cited by other articles:


Home page
 J ANIM SCIHome page
D. C. Kendall, A. M. Gaines, B. J. Kerr, and G. L. Allee
True ileal digestible tryptophan to lysine ratios in ninety- to one hundred twenty-five-kilogram barrows
J Anim Sci, November 1, 2007; 85(11): 3004 - 3012.
[Abstract] [Full Text] [PDF]

Home page
 J ANIM SCIHome page
A. C. Guzik, J. O. Matthews, B. J. Kerr, T. D. Bidner, and L. L. Southern
Dietary tryptophan effects on plasma and salivary cortisol and meat quality in pigs
J Anim Sci, August 1, 2006; 84(8): 2251 - 2259.
[Abstract] [Full Text] [PDF]

Home page
 J ANIM SCIHome page
Y. Z. Li, B. J. Kerr, M. T. Kidd, and H. W. Gonyou
Use of supplementary tryptophan to modify the behavior of pigs
J Anim Sci, January 1, 2006; 84(1): 212 - 220.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
J.-W. Park, Y.-B. Choi, S.-K. Park, Y.-I. Kim, and K.-S. Lee
Magnetic Resonance Imaging Reveals Selective Vulnerability of the Cerebellum and Basal Ganglia in Malignant Hyperthermia
Arch Neurol, September 1, 2004; 61(9): 1462 - 1463.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1993 by the American Society of Animal Science.