Journal of Animal Science, Vol 71, Issue 11 3020-3024, Copyright © 1993 by American Society of Animal Science

JOURNAL ARTICLE

Growth and plasma zinc responses of young pigs fed pharmacologic levels of zinc

J. D. Hahn and D. H. Baker
Department of Animal Sciences, University of Illinois, Urbana 61801.

Three trials were conducted to evaluate high levels of Zn addition from various Zn sources on growth performance and plasma Zn responses of 8-kg pigs. Zinc supplements were added to 20% CP starting diets (125 mg of Zn/kg) containing antibiotics. Trial 1 was done to evaluate plasma Zn responses of pigs fed three different feed-grade Zn sources: ZnO where supplemental Zn levels were 0, 250, 500, 1,000, 3,000, and 5,000 mg/kg; ZnSO4 at 1,500 or 2,500 mg of Zn/kg; and a zinc-lysine complex (Zn-Lys) at 1,500 or 2,500 mg of Zn/kg. Plasma Zn concentration as a function of supplemental Zn intake was fitted to a broken-line for ZnO data and to simple linear models for ZnSO4 and Zn-Lys data. For ZnO, plasma Zn did not increase until concentrations > 1,000 mg Zn/kg were fed. Above this level, plasma Zn increased linearly (P < .01) for all three sources of Zn, although slopes of the ZnO and Zn-Lys response curves were 56% (P < .05) and 110%, respectively, of the ZnSO4 slopes. In Trial 2, five diets were fed: basal, 3,000 and 5,000 mg of Zn/kg from ZnO, and 3,000 and 5,000 mg of Zn/kg from ZnSO4. Daily gain and daily feed intake were increased (P < .05) by ZnO addition, regardless of level, whereas ZnSO4 addition increased these performance indices only at the 3,000 mg of Zn/kg level of supplementation. Plasma Zn responses to ZnSO4 addition were almost double those of ZnO addition.(ABSTRACT TRUNCATED AT 250 WORDS)

This article has been cited by other articles:

				R. L. Payne, T. D. Bidner, T. M. Fakler, and L. L. Southern Growth and intestinal morphology of pigs from sows fed two zinc sources during gestation and lactation J Anim Sci, August 1, 2006; 84(8): 2141 - 2149. [Abstract] [Full Text] [PDF]

				X. Li, J. Yin, D. Li, X. Chen, J. Zang, and X. Zhou Dietary Supplementation with Zinc Oxide Increases IGF-I and IGF-I Receptor Gene Expression in the Small Intestine of Weanling Piglets J. Nutr., July 1, 2006; 136(7): 1786 - 1791. [Abstract] [Full Text] [PDF]

				M. J. Rincker, G. M. Hill, J. E. Link, A. M. Meyer, and J. E. Rowntree Effects of dietary zinc and iron supplementation on mineral excretion, body composition, and mineral status of nursery pigs J Anim Sci, December 1, 2005; 83(12): 2762 - 2774. [Abstract] [Full Text] [PDF]

				C. E. Buff, D. W. Bollinger, M. R. Ellersieck, W. A. Brommelsiek, and T. L. Veum Comparison of growth performance and zinc absorption, retention, and excretion in weanling pigs fed diets supplemented with zinc-polysaccharide or zinc oxide J Anim Sci, October 1, 2005; 83(10): 2380 - 2386. [Abstract] [Full Text] [PDF]

				G. R. Hollis, S. D. Carter, T. R. Cline, T. D. Crenshaw, G. L. Cromwell, G. M. Hill, S. W. Kim, A. J. Lewis, D. C. Mahan, P. S. Miller, et al. Effects of replacing pharmacological levels of dietary zinc oxide with lower dietary levels of various organic zinc sources for weanling pigs J Anim Sci, September 1, 2005; 83(9): 2123 - 2129. [Abstract] [Full Text] [PDF]

				O. Hojberg, N. Canibe, H. D. Poulsen, M. S. Hedemann, and B. B. Jensen Influence of Dietary Zinc Oxide and Copper Sulfate on the Gastrointestinal Ecosystem in Newly Weaned Piglets Appl. Envir. Microbiol., May 1, 2005; 71(5): 2267 - 2277. [Abstract] [Full Text] [PDF]

				S. B. Williams, L. L. Southern, and T. D. Bidner Effects of supplemental dietary phytase and pharmacological concentrations of zinc on growth performance and tissue zinc concentrations of weanling pigs J Anim Sci, February 1, 2005; 83(2): 386 - 392. [Abstract] [Full Text] [PDF]

				N. R. Augspurger, J. D. Spencer, D. M. Webel, and D. H. Baker Pharmacological zinc levels reduce the phosphorus-releasing efficacy of phytase in young pigs and chickens J Anim Sci, June 1, 2004; 82(6): 1732 - 1739. [Abstract] [Full Text] [PDF]

				M. S. Carlson, C. A. Boren, C. Wu, C. E. Huntington, D. W. Bollinger, and T. L. Veum Evaluation of various inclusion rates of organic zinc either as polysaccharide or proteinate complex on the growth performance, plasma, and excretion of nursery pigs J Anim Sci, May 1, 2004; 82(5): 1359 - 1366. [Abstract] [Full Text] [PDF]

				M. Roselli, A. Finamore, I. Garaguso, M. S. Britti, and E. Mengheri Zinc Oxide Protects Cultured Enterocytes from the Damage Induced by Escherichia coli J. Nutr., December 1, 2003; 133(12): 4077 - 4082. [Abstract] [Full Text] [PDF]

				E. van Heugten, J. W. Spears, E. B. Kegley, J. D. Ward, and M. A. Qureshi Effects of organic forms of zinc on growth performance, tissue zinc distribution, and immune response of weanling pigs J Anim Sci, August 1, 2003; 81(8): 2063 - 2071. [Abstract] [Full Text] [PDF]

				A. Owusu-Asiedu, C. M. Nyachoti, and R. R. Marquardt Response of early-weaned pigs to an enterotoxigenic Escherichia coli (K88) challenge when fed diets containing spray-dried porcine plasma or pea protein isolate plus egg yolk antibody, zinc oxide, fumaric acid, or antibiotic J Anim Sci, July 1, 2003; 81(7): 1790 - 1798. [Abstract] [Full Text] [PDF]

				C. L. Case and M. S. Carlson Effect of feeding organic and inorganic sources of additional zinc on growth performance and zinc balance in nursery pigs J Anim Sci, July 1, 2002; 80(7): 1917 - 1924. [Abstract] [Full Text] [PDF]

				F. Brinkhaus, J. Mann, C. Zorich, and J. A. Greaves Bioavailability of Zinc Propionate in Dogs J. Nutr., December 1, 1998; 128(12): 2596S - 2596. [Full Text]