J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lindemann, M. D.
Right arrow Articles by Schurig, G. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lindemann, M. D.
Right arrow Articles by Schurig, G. G.

Journal of Animal Science, Vol 71, Issue 1 171-178, Copyright © 1993 by American Society of Animal Science

JOURNAL ARTICLE

Potential ameliorators of aflatoxicosis in weanling/growing swine

M. D. Lindemann, D. J. Blodgett, E. T. Kornegay and G. G. Schurig
Department of Animal Science, Virginia Polytechnic Institute and State University, Blacksburg 24061.

Three trials using 207 crossbred pigs were conducted to evaluate the effects of aflatoxin-contaminated corn on young pigs and to determine whether several nutritional and nonnutritional dietary amendments would benefit performance or health in situations of aflatoxin B1 contamination. In Trial 1 using 90 pigs in a 49-d trial, linear (P < .01) and quadratic (P < .05) decreases in ADG were observed with increasing (0, 420, 840 ppb) dietary aflatoxin level. This growth decrease was associated with linear reductions (P < .01) in ADFI and decreases in gain/feed. Serum indicators of protein synthetic capabilities and of liver damage were also adversely affected. Improvements in growth rate for the total trial period in the presence of 840 ppb of aflatoxin were obtained with the addition of the 2 ppm of folic acid (P < .05) or .5% hydrated sodium calcium aluminosilicate (HSCA) (P < .01); the magnitude of improvement was greater for the HSCA. The addition of HSCA to the contaminated diet also restored the serum clinical chemistry profile to that exhibited by pigs fed the diet without contaminated corn. The addition of .6 ppm of Se to a basal diet containing .3 ppm of Se was generally without effect. In Trial 2, 63 pigs were used in a 42-d trial to further assess the effectiveness of both folic acid and HSCA, as well as of two sodium bentonites, in reducing the effects of aflatoxin from naturally contaminated diets (800 ppb of aflatoxin). Folic acid had no positive effect in this trial, but HSCA improved ADG (P < .01) and all clinical chemistry indicators that had been negatively affected by the contaminated diet (P < .05).(ABSTRACT TRUNCATED AT 250 WORDS)


This article has been cited by other articles:


Home page
 Toxicol Ind HealthHome page
H. Turkez and T. Sisman
Anti-genotoxic effect of hydrated sodium calcium aluminosilicate on genotoxicity to human lymphocytes induced by aflatoxin B1
Toxicology and Industrial Health, March 1, 2007; 23(2): 83 - 89.
[Abstract] [PDF]

Home page
 J ANIM SCIHome page
P. N. Thompson, A. Stone, and W. A. Schultheiss
Use of treatment records and lung lesion scoring to estimate the effect of respiratory disease on growth during early and late finishing periods in South African feedlot cattle
J Anim Sci, February 1, 2006; 84(2): 488 - 498.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Poult. Res.Home page
C. A. Bailey, G. W. Latimer, A. C. Barr, W. L. Wigle, A. U. Haq, J. E. Balthrop, and L. F. Kubena
Efficacy of Montmorillonite Clay (NovaSil PLUS) for Protecting Full-Term Broilers from Aflatoxicosis
J. Appl. Poult. Res., January 1, 2006; 15(2): 198 - 206.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1993 by the American Society of Animal Science.