J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Chew, B. P.
Right arrow Articles by Heirman, L. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chew, B. P.
Right arrow Articles by Heirman, L. R.

Journal of Animal Science, Vol 69, Issue 12 4892-4897, Copyright © 1991 by American Society of Animal Science

JOURNAL ARTICLE

Subcellular distribution of beta-carotene, retinol, and alpha-tocopherol in porcine lymphocytes after a single injection of beta-carotene

B. P. Chew, T. S. Wong, J. J. Michal, F. E. Standaert and L. R. Heirman
Dept. of Anim. Sci. Washington State University, Pullman 99164-6320.

The subcellular distribution of beta-carotene, retinol, and alpha-tocopherol in lymphocytes was studied in pigs (50 to 55 kg) injected once with 0, 20, or 40 mg of beta-carotene. Blood was sampled at 0, 24, 48, and 72 h postinjection. Plasma beta-carotene in treated pigs peaked at 24 h and decreased rapidly thereafter. Beta-carotene was found in all subcellular fractions of lymphocytes. Concentrations in nuclei mirrored changes in plasma. However, beta-carotene in mitochondria and cytosol peaked at 24 h, whereas that in microsomes peaked at 48 h. Concentrations in the latter three subcellular fractions remained high at 48 and 72 h even though plasma beta-carotene had decreased to very low concentrations. Peak concentrations of beta-carotene were highest in the nuclei, intermediate in the mitochondria and microsomes, and lowest in the cytosol. Treatment did not influence concentrations of retinol or alpha-tocopherol in the various subcellular fractions. These data provide more compelling evidence for the possible role of beta-carotene in lymphocytes.


This article has been cited by other articles:


Home page
 J. Nutr.Home page
B. P. Chew and J. S. Park
Carotenoid Action on the Immune Response
J. Nutr., January 1, 2004; 134(1): 257S - 261.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
E. A. Koutsos, A. J. Clifford, C. C. Calvert, and K. C. Klasing
Maternal Carotenoid Status Modifies the Incorporation of Dietary Carotenoids into Immune Tissues of Growing Chickens (Gallus gallus domesticus)
J. Nutr., April 1, 2003; 133(4): 1132 - 1138.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
B. P. Chew, J. S. Park, B. C. Weng, T. S. Wong, M. G. Hayek, and G. A. Reinhart
Dietary {beta}-Carotene Absorption by Blood Plasma and Leukocytes in Domestic Cats
J. Nutr., September 1, 2000; 130(9): 2322 - 2325.
[Abstract] [Full Text]

Home page
 J. Nutr.Home page
B. P. Chew, J. S. Park, B. C. Weng, T. S. Wong, M. G. Hayek, and G. A. Reinhart
Dietary {beta}-Carotene Is Taken up by Blood Plasma and Leukocytes in Dogs
J. Nutr., July 1, 2000; 130(7): 1788 - 1791.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1991 by the American Society of Animal Science.