Journal of Animal Science, Vol 69, Issue 11 4505-4511, Copyright © 1991 by American Society of Animal Science

JOURNAL ARTICLE

Toxicity and tissue accumulation of copper in chicks fed casein and soy-based diets

M. A. Funk and D. H. Baker
Dept. of Anim. Sci., University of Illinois, Urbana 61801.

Experiments were conducted to study Cu toxicity in chicks fed casein or soy-containing diets containing graded levels of excess CuSO4.5H2O. Differences between diets in measures of Cu toxicity were pronounced. Addition of 800 mg of Cu/kg to a casein-dextrose semipurified diet decreased weight gains by 63%, but the same addition of Cu to a corn-soybean meal complex diet decreased gains by only 8%. At all levels of Cu supplementation (100, 200, 400 or 800 mg/kg), Cu deposition in the liver was increased markedly in chicks fed casein diets compared with those fed the complex diet. Substituting soy-protein concentrate for casein in the semipurified diet resulted in a marked decrease in Cu toxicity as measured by weight gain reductions and tissue accumulation of Cu.

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