Journal of Animal Science, Vol 69, Issue 10 4019-4029, Copyright © 1991 by American Society of Animal Science

JOURNAL ARTICLE

Influence of dietary protein and recombinant porcine somatotropin administration in young pigs: II. Accretion rates of protein, collagen, and fat

T. J. Caperna, D. R. Komarek, D. Gavelek and N. C. Steele
US Department of Agriculture, Beltsville, MD 20705.

The present study was conducted to determine the effects of different dietary protein levels and recombinant porcine somatotropin (rpST) administration on deposition rates of protein, fat, water, ash, and collagen in pigs. Ten groups of six barrows (30 kg BW) were restrictively fed (80% of ad libitum) one of five diets containing 11, 15, 19, 23, or 27% CP. Diets were isoenergetic and all contained equivalent amounts of lysine. Thirty barrows were treated daily with rpST (100 micrograms/kg) by i.m. injection; remaining pigs were treated with diluent for 42 d. At all levels of dietary protein intake, carcass and empty body accretion rates of protein, water, and ash were greater in rpST-treated pigs than in respective controls. The magnitude of change elicited by rpST was lowest in pigs consuming 11% CP. Administration of rpST resulted in a 34% decrease in the accretion rate of fat; increasing protein intake resulted in a linear decrease in fat accretion in control and rpST-treated pigs. Accretion rates of protein, water, ash, and fat were increased in viscera of rpST-treated pigs compared with respective controls; rates of visceral protein and water accretion were increased as dietary protein was increased, whereas deposition of fat was decreased in control and rpST-treated pigs. Administration of rpST resulted in an overall 66% increase in the utilization efficiency of dietary protein for empty body protein deposition. Protein intake had minimal effect on the concentration of collagen in the carcass; however, rpST treatment increased concentrations of total and soluble collagen by 30 and 33%, respectively. Recombinant pST had little influence on collagen crosslinking or maturation. Deposition rate of carcass collagen was increased 63% in rpST-treated pigs compared with respective controls.

This article has been cited by other articles:

				F. A. Wilson, A. Suryawan, R. A. Orellana, H. V. Nguyen, A. S. Jeyapalan, M. C. Gazzaneo, and T. A. Davis Fed levels of amino acids are required for the somatotropin-induced increase in muscle protein synthesis Am J Physiol Endocrinol Metab, October 1, 2008; 295(4): E876 - E883. [Abstract] [Full Text] [PDF]

				F. A. Wilson, R. A. Orellana, A. Suryawan, H. V. Nguyen, A. S. Jeyapalan, J. Frank, and T. A. Davis Stimulation of muscle protein synthesis by somatotropin in pigs is independent of the somatotropin-induced increase in circulating insulin Am J Physiol Endocrinol Metab, July 1, 2008; 295(1): E187 - E194. [Abstract] [Full Text] [PDF]

				T. A. Davis, J. A. Bush, R. C. Vann, A. Suryawan, S. R. Kimball, and D. G. Burrin Somatotropin regulation of protein metabolism in pigs J Anim Sci, January 1, 2004; 82(13_suppl): E207 - 213. [Abstract] [Full Text] [PDF]

				R. M. Blome, J. K. Drackley, F. K. McKeith, M. F. Hutjens, and G. C. McCoy Growth, nutrient utilization, and body composition of dairy calves fed milk replacers containing different amounts of protein J Anim Sci, June 1, 2003; 81(6): 1641 - 1655. [Abstract] [Full Text] [PDF]

				J. A. Bush, S. R. Kimball, P. M. J. O'Connor, A. Suryawan, R. A. Orellana, H. V. Nguyen, L. S. Jefferson, and T. A. Davis Translational Control of Protein Synthesis in Muscle and Liver of Growth Hormone-Treated Pigs Endocrinology, April 1, 2003; 144(4): 1273 - 1283. [Abstract] [Full Text] [PDF]

				J. A. Bush, D. G. Burrin, A. Suryawan, P. M. J. O'Connor, H. V. Nguyen, P. J. Reeds, N. C. Steele, J. B. Van Goudoever, and T. A. Davis Somatotropin-induced protein anabolism in hindquarters and portal-drained viscera of growing pigs Am J Physiol Endocrinol Metab, February 1, 2003; 284(2): E302 - E312. [Abstract] [Full Text] [PDF]

				J. A. Bush, G. Wu, A. Suryawan, H. V. Nguyen, and T. A. Davis Somatotropin-Induced Amino Acid Conservation in Pigs Involves Differential Regulation of Liver and Gut Urea Cycle Enzyme Activity J. Nutr., January 1, 2002; 132(1): 59 - 67. [Abstract] [Full Text] [PDF]

				C. C. Metges Does Dietary Protein in Early Life Affect the Development of Adiposity in Mammals? J. Nutr., July 1, 2001; 131(7): 2062 - 2066. [Abstract] [Full Text] [PDF]

				V. Y. Hayes, R. J. Urban, J. Jiang, T. J. Marcell, K. Helgeson, and N. Mauras Recombinant Human Growth Hormone and Recombinant Human Insulin-Like Growth Factor I Diminish the Catabolic Effects of Hypogonadism in Man: Metabolic and Molecular Effects J. Clin. Endocrinol. Metab., May 1, 2001; 86(5): 2211 - 2219. [Abstract] [Full Text]