J. Anim Sci.
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Journal of Animal Science, Vol 68, Issue 5 1337-1345, Copyright © 1990 by American Society of Animal Science

JOURNAL ARTICLE

Humoral and cell-mediated immune response and performance of weaned pigs fed four supplemental vitamin E levels and housed at two nursery temperatures

E. D. Bonnette, E. T. Kornegay, M. D. Lindemann and C. Hammerberg
Virginia Polytechnic Institute and State University, Blacksburg 24061.

Three trials using 80 Yorkshire x Hampshire x Duroc crossbred pigs (avg initial wt, 6.9 kg) were conducted to determine the effects of four dietary vitamin E levels (11, 110, 220 and 550 IU/kg of feed) on the humoral and cell-mediated immune response and performance of 4-wk-old weanling pigs housed at two nursery temperatures (19 or 30 degrees C). Interactive effects of temperature and vitamin E were not observed for any measurements. Serum and liver vitamin E levels increased linearly with increasing level of dietary vitamin E, but performance, cortisol, antibody levels and mitogen-induced stimulation indices were not affected by supplemental levels of vitamin E. Average daily gain and feed intake were higher (P less than .01) for pigs housed at 19 degrees C than for pigs housed at 30 degrees C, but feed:gain ratios, mitogen stimulation index of white blood cells, plasma cortisol levels and antibody titers were not altered. Although supplemental vitamin E above the NRC estimated requirement increased serum and liver vitamin E concentrations, no differences were observed in humoral and cell-mediated immune response, cortisol levels or performance for weanling pigs housed at either 19 or 30 degrees C temperatures.


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Copyright © 1990 by the American Society of Animal Science.