J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yen, J. T.
Right arrow Articles by Pond, W. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yen, J. T.
Right arrow Articles by Pond, W. G.

Journal of Animal Science, Vol 68, Issue 12 4236-4242, Copyright © 1990 by American Society of Animal Science

JOURNAL ARTICLE

Effect of carbadox on net absorption of ammonia and glucose into hepatic portal vein of growing pigs

J. T. Yen and W. G. Pond
U.S. Department of Agriculture, Clay Center, NE 68933.

Chronic cannulas were placed into the hepatic portal vein, ileal vein and carotid artery of growing pigs trained to consume their daily allowance of 1.2 kg of feed (16% protein corn-soybean meal basal diet) in a single meal. The average preoperative BW of pigs was 44.7 kg for Trial 1 (three pigs) and 35.3 kg for Trial 2 (seven pigs). In Trial 1, net absorption of ammonia (NH3) and glucose into the portal vein was determined three times at weekly intervals. The net portal absorptions were derived by multiplying the porto-arterial plasma concentration difference of NH3 and glucose by portal vein plasma flow rate estimated with the p-aminohippuric acid indicator-dilution technique. Differences in the net portal absorptions of NH3 and glucose among the three weekly measurements were small (P greater than .05). In Trial 2, the first sequence of net portal absorption measurements was conducted when pigs were fed the basal diet, and the second sequence of measurements was conducted after the pigs had been fed the diet supplemented with 55 ppm of carbadox for 7 d. Carbadox supplementation reduced (P less than .05) plasma NH3 concentration in portal plasma during the 2.5-h to 5-h postprandial period and decreased (P less than .05) net portal absorption of NH3 during the 2.5-h to 4-h postprandial period. Carbadox, however, did not affect (P greater than .05) net portal absorption of glucose. We suggest that carbadox suppresses the production of cell-toxic NH3 by intestinal microorganisms and, thus, reduces the injury and turnover of intestinal cells.(ABSTRACT TRUNCATED AT 250 WORDS)


This article has been cited by other articles:


Home page
 J ANIM SCIHome page
M. C. Walsh, D. M. Sholly, R. B. Hinson, K. L. Saddoris, A. L. Sutton, J. S. Radcliffe, R. Odgaard, J. Murphy, and B. T. Richert
Effects of water and diet acidification with and without antibiotics on weanling pig growth and microbial shedding
J Anim Sci, July 1, 2007; 85(7): 1799 - 1808.
[Abstract] [Full Text] [PDF]

Home page
 J ANIM SCIHome page
J. T. Yen, V. H. Varel, and J. A. Nienaber
Metabolic and microbial responses in western crossbred and Meishan growing pigs fed a high-fiber diet
J Anim Sci, June 1, 2004; 82(6): 1740 - 1755.
[Abstract] [Full Text] [PDF]

Home page
 J ANIM SCIHome page
J. T. Yen, B. J. Kerr, R. A. Easter, and A. M. Parkhurst
Difference in rates of net portal absorption between crystalline and protein-bound lysine and threonine in growing pigs fed once daily
J Anim Sci, April 1, 2004; 82(4): 1079 - 1090.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1990 by the American Society of Animal Science.