J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Marzo, F.
Right arrow Articles by Santidrian, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Marzo, F.
Right arrow Articles by Santidrian, S.

Journal of Animal Science, Vol 68, Issue 10 3306-3312, Copyright © 1990 by American Society of Animal Science

JOURNAL ARTICLE

Effect of tannic acid on the immune response of growing chickens

F. Marzo, A. Tosar and S. Santidrian
Dept. of Histology, University of Navarra, Pamplona, Spain.

Effects of tannic acid (TA) on the immune response of growing chickens were studied in two experiments. In the first experiment, 25 or 30 g TA/kg diet was added to a control diet; added TA reduced (P less than .05) weight gain, protein efficiency rate and weight of bursa of Fabricius, thymus and spleen. Total IgM and IgG immunoglobulin levels (primary and secondary immune responses) against killed Brucella abortus were reduced in TA-fed chickens. Numbers of total white blood cells and absolute lymphocytes also were reduced. Tannic acid feeding also resulted in the involution of bursal follicles. In second experiment, TA-treated birds were challenged with a live culture of Brucella abortus. The total IgM and IgG levels again were depressed along with lymphoid organ weights of treated birds. Persistence of B. abortus in spleens of TA-treated birds was higher. These data suggest that the administration of tannic acid impairs the immune function of growing chickens in a dose-dependent manner.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1990 by the American Society of Animal Science.