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Lysocellin Effects on Growth Performance, Ruminal Fermentation, Nutrient Digestibility and Nitrogen Metabolism in Steers Fed Forage Diets^1,2,

North Carolina State University, Raleigh 27695-7621 and Pitman-Moore Inc.,, Terre Haute, IN 47808

Abstract

Studies were conducted to determine the effects of lysocellin on growth performance and metabolism of steers fed forage-based diets. Treatments in all experiments consisted of 1) control, 2) 100 mg lysocellin/d, 3) 200 mg lysocellin/d and 4) 200 mg monensin/d. In each of two 90-d performance studies, 24 Hereford steers were individually fed greenchop (fungus-free tall fescue and Coastal and Tifton-44 bermudagrass) ad libitum and .91 kg/d of a corn-trace mineral salt supplement. In Exp. 1, tall fescue was fed from d 1 to 45 and bermudagrass from d 46 to 90. Bermudagrass was offered during d 1 to 45 and tall fescue during d 46 to 90 in Exp. 2. Lysocellin improved gain (Exp. 1, P < .01) and feed conversion (Exp. 1 and 2 combined, P < .05), decreased total VFA concentrations (P < .05), increased molar proportions of propionate, isobutyrate and isovalerate (P < .01), decreased molar proportions of acetate and butyrate (P < .01) and lowered acetate: propionate (P < .01). Two metabolism studies involving a total of 16 Hereford steers were conducted. Steers were fed tall fescue greenchop and .91 kg/d supplement for a 34-d adjustment period followed by a 5-d total collection period. Lysocellin increased N digestibility (P < .01) and N retention (P < .06) but did not (P > .05) affect DM, NDF or ADF digestibility. Data indicate that lysocellin results in major alterations in ruminal fermentation and can increase growth performance and N retention in steers fed forage-based diets.

¹ Paper No. 11683 of the journal series of the North Carolina ARS, Raleigh 7695-7601. Use of trade names in this publication does not imply endorsement by the North Carolina ARS or by USDA, ARS, or criticism of similar products not mentioned. The authors express their appreciation to D. Askew, T. Nowell, S. Ray and G. Ryan for assistance in sample collections and animal care, S. West for statistical analysis and L. Samsell and E. Leonard for analytical work.

² Supported in part by a grant from PitmanMoore, Inc., Terre Haute, IN.

³ Dept. of Anim. Sci. and Interdept. Nutr. Program, North Carolina State Univ.

⁴ USDA, ARS and Dept. of Crop Sci. and Anim. Sci.

⁵ Pitman-Moore, Inc.