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Effects of Dietary Level and Withdrawal Time on the Efficacy of Cimaterol as a Growth Repartitioning Agent in Finishing Swine¹

University of Kentucky, Lexington 40546 and American Cyanamid Company, Princeton, NJ 08540

Abstract

Hampshire-Yorkshire pigs were used to evaluate the efficacy of the beta-adrenergic agonist cimaterol on performance and carcass characteristics and to determine whether the length of withdrawal period influenced the response to cimaterol. The basal diet was an unmedicated corn-soybean meal diet (14% CP) fortified with minerals and vitamins. Treatments were the basal diet, the basal plus .25 ppm cimaterol with a 1-, 3- or 5-d withdrawal period and the basal plus .5 ppm cimaterol with a 1-d withdrawal period prior to slaughter. Each diet was fed to eight pen-replicates of five pigs/pen from 62 to 107 kg. Growth rate and efficiency of feed utilization were improved (P < .03) by cimaterol. Pigs fed .5 ppm cimaterol tended to be less sound on their feet and legs (P < .10) and to have more hoof cracks and pad abrasions than controls. Carcass yield, backfat, longissimus area and calculated muscle percentage were improved (P < .05) by cimaterol, with the decrease in 10th rib fat depth (P < .10) and increase in percentage of muscle (P < .05) being greater for the .5 vs .25 ppm level of cimaterol. In pigs fed cimaterol, the proportion of fat in the longissimus was decreased (P < .05), whereas protein was increased (P < .10). Cimaterol is an effective repartitioning agent for pigs with the .5 ppm level being more effective than the .25 ppm level in improving carcass leanness and muscling, but resulting in more feet and leg unsoundness. A 3-or 5-d withdrawal of the .25 ppm level of cimaterol did not reduce its effectiveness.

¹ Journal paper no. 88-5-27 of the Kentucky Agric. Exp. Sta. The research was partially supported by a grant-in-aid from American Cyanamid Co., Princeton, NJ 08540. Appreciation is extended to J. R. May and H. J. Monegue for assistance in conducting the study.

² Dept. of Anim. Sci., Univ. of Kentucky.

³ American Cyanamid Co.

⁴ CL 263,780; American Cyanamid Co., Princeton, NJ. 08540.