J. Anim Sci.
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J. Anim Sci. 1988. 66:2084-2090.
© 1988 American Society of Animal Science
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Immunomodulation: A Means of Disease Prevention in Stressed Livestock1

Frank Blecha

Kansas State University2, Manhattan 66506

Abstract

The ability to stimulate the immune response of cattle and pigs offers a new means of disease intervention. This review discusses current in vivo experiments that have evaluated immunomodulators in cattle and pigs. Levamisole, thiabendazole, imuthiol, avridine, isoprinosine, bovine recombinant interferon, human recombinant interleukin-2, bovine recombinant interleukin-2 and various supplemental vitamins and minerals have been used as immunomodulators in livestock with various degrees of success. Future research on immunomodulators, specific for domestic farm animals, will provide additional methods of treating immunosuppressed animals.

Footnotes

1 Research from this laboratory was supported in part by grants from the USDA (84-CRSR-2-2411, 86-CRCR-1-1957, and 87-CRCR-1-2309). Published as contribution 88-119-J of the Kansas Agric. Exp. Sta. This paper was presented at the 79th Annu. Mtg. of Am. Soc. Anim. Sci. at Logan, UT in a symposium entitled "Environmental and Behavioral Influences on Immunocompetence."

2 College of Vet. Med., Dept. of Anat. and Physiol.




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