J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J. Anim Sci. 1988. 66:1538-1547.
© 1988 American Society of Animal Science
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pullen, D. L.
Right arrow Articles by Ames, N. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pullen, D. L.
Right arrow Articles by Ames, N. K.

Turnover of Hepatic and Plasma Triacylglycerol in Sheep1

D. L. Pullen2, R. S. Emery3 and N. K. Ames4

Michigan State University, East Lansing 48824

Abstract

Contributions of the intestine and liver to triaclyglycerol (TG) formation from endogenous fatty acids were investigated in sheep. Cannulation and sampling of the intestinal lymph ducts and portal veins of two mature, nonpregnant ewes followed by an i.v. dose of 100 µCi of [14C] palmitate into a mesenteric cannula suggested intestinal contribution to endogenous TG production to be of no consequence. Turnover rates of TG within the plasma, hepatic microsomal and hepatic fat droplet compartments of four wethers averaged 20 ± 8, 7.8 ± 1.5 and 2.3 ± .8 mg · h-1 · kg body weight-1, respectively. A large, relatively inert pool of fat droplets with a slow turnover contained between 80 and 90% of the total hepatic TG. Hepatic TG concentration and turnover rates within the hepatic microsomal and fat droplet pools were inversely (r = -.86) and positively (r = .99) correlated, respectively, indicating that hepatic secretion of TG as lipoprotein was decreased as hepatic TG concentration increased. The model developed from these figures suggest that 40% of the plasma TG turnover is of endogenous origin and that this percentage value decreases when hepatic TG content is increased.

Footnotes

1 Published with the approval of the Director of the Michigan Agric. Exp. Sta. as Journal Article No. 12438.

2 Current address: Young's Inc., Roaring Spring, PA 16673.

3 Dept. of Anim. Sci.

4 School of Vet. Med.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1988 by the American Society of Animal Science.