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Effects of Salinomycin on Sow Weight Change during Lactation and on Sow Reproductive Performance^1,2,

University of Illinois³, Urbana 61801

Abstract

Forty-five gravid cross-bred sows (mean parity 3.3 ± .3) were randomly allotted to two dietary treatments: corn-soybean meal (CS) or CS plus 60 mg salinomycin per kilogram of diet (CSS). Sows were fed their respective diets through two successive parities with dietary treatment initiated at 100 d postcoitum and continued until weaning of the second successive litter. Therefore, sows fed CSS received salinomycin for 14 d before the first parturition and for approximately 153 d before the second parturition. Daily feed intake was restricted to 2 kg·hd^–1·d^–1 during gestation and to 3 kg·hd^–1·d^–1 from weaning to breeding. All sows had ad libitum access to feed during lactation. Sows were weighed 7 d prior to parturition, at weaning and at breeding. Weaning-to-estrus interval and farrowing interval were recorded for all sows. Litters were weighed at birth and weaning. There were no differences (P > .05) between dietary treatments in sow weights before parturition, at weaning or at breeding for either first or second farrowing. The CSS-fed sows lost more weight from weaning to breeding after the first (P < .03) and second (P < .05) lactation periods than CS-fed sows. The CSS-fed sows tended to gain more (P = .06) weight during lactation than CS-fed sows. There were no differences (P > .05) between treatments in lactation feed intake, weaning-to-estrus interval, farrowing interval, litter size born or weaned, litter weights at birth or at weaning, or in sow culling rate. CSS-fed sows farrowed fewer (P < .04) dead piglets than did CS-fed sows during the first farrowing. Feeding salinomycin to parity-3 sows had no effect on weight gain or loss during lactation or during the weaning to rebreeding period, nor did it affect reproductive performance.

¹ Supported by an unrestricted research gift from Pfizer International, Inc., New York, NY 10017.

² The authors gratefully acknowledge the assistance of Sam Carmer, Eric Parr and Fred Cox in completing this research work.

³ Depts. of Vet. Clin. Med. (Bane, Hall) and Biosci. (Bevill), College of Vet. Med.

⁴ Salinomycin is an investigational new animal drug that is currently not cleared by the Food and Drug Administration for use in swine. Salinomycin premix was supplied by A. H. Robbins, Co., Richmond, VA 23261.