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University of Illinois, Urbana 61801 and Lilly Research Laboratories, Greenfield, IN 46140
Abstract
Levels of aggression, activity and performance were determined in 270 pigs (initial wt 29.8 kg) injected with amperozide (1.0 mg/kg i.m.), azaperone (2.2 mg/kg i.m.) or saline (.1 ml/kg i.m.) immediately prior to mixing. Pigs had ad libitum access to feed in pens of 15, and six pens were allotted to each treatment. Each pen was video-taped for 48 h after injection. Aggression was determined by continuous observation and summarized for each 2-h period. Injuries on the ears and shoulders of each pig were scored prior to injection and 1,2,3 and 7 d after treatment. Eating, drinking and lying were determined by scan sampling at 2-min intervals and summarized for each 2-h period. Weight gain, feed consumption and efficiency were determined for periods ending on d 3, 7, 14, 28, 42, 56, 70 and 84. Both drugs reduced total fighting from 309.8 min for saline to 190.7 and 189.6 min for amperozide- and azaperone-treated pens, respectively (P < .01). Treatment differences in aggression and lying were evident during the initial 6 h only. Amperozide resulted in fewer fights involving two pigs (197.3/pen) than did azaperone (260.2/pen) or saline (298.3/pen) (P < .05). Injuries to the ears (P < .01) and total injuries (P < .05) were less severe in amperozide-treated pigs than in pigs on the other treatments. Amperozide-treated pigs spent less time eating on d 1 than did saline- or azaperone-treated pigs (106.1 vs 139.2 and 161.3 min/d, respectively; P < .01) but compensated on d 2 (P < .05) such that total eating time in 2 d did not differ. Weight gain, feed consumption and efficiency were similar for all treatments during each period of the trial. Both drugs reduced agonistic behavior but had no effect on performance.
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