J. Anim Sci.
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J. Anim Sci. 1985. 61:782-788.
© 1985 American Society of Animal Science
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The Efficacy of Salinomycin as a Growth Promotant for Swine from 9 to 97 kg1,2,

M. D. Lindemann3, E. T. Kornegay3, T. S. Stahly4, G. L. Cromwell4, R. A. Easter5, B. J. Kerr5 and D. M. Lucas6

Virginia Polytechnic Institute and State University, Blacksburg 24061; , University of Kentucky, Lexington 40546; , University of Illinois, Urbana 61801 and and A. H. Robins Company, Richmond, VA 23261

Abstract

Six trials involving 586 pigs initially averaging 9 kg were conducted at three locations (two trials/location) to evaluate the effects of the dietary addition of 0, 27.5, 55, 82.5 and 110 ppm of a monocarboxylic polyether antibiotic, salinomycin, on feed intake, growth rate and feed efficiency of swine fed corn-soybean meal-based diets. Over the total trial (9 to 97 kg), quadratic improvements in gain (P<.01) and feed:gain (P<.04) occurred with increasing level of salinomycin, but feed intake was not affected (P>.25). Mean improvements for all drug levels over control values for the total trial were 4.3% for daily gain (P>.01) and 3.4% for feed:gain (P<.01). For the total trial, rate and efficiency of gain were optimized in pigs fed the 82.5-ppm level of salinomycin with an improvement of 5.2% in daily gain and 4.8% in feed:gain over pigs fed the control diet. The absence of any significant trial x treatment interaction suggests that the nature of the response was not dependent on differences in environment, management or other factors that existed among trial locations.

Footnotes

1 Salinomycin is an Investigational New Animal Drug that is currently not cleared by the Food and Drug Administration for use in swine.

2 Supported in part by a grant-in-aid by A. H. Robins Co., Richmond, VA 23261.

3 Dept. of Anim. Sci., Virginia Polytechnic Institute and State Univ.

4 Dept. of Anim. Sci., Univ. of Kentucky.

5 Dept. of Anim. Sci., Univ. of Illinois.

6 A. H. Robins Co.






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Copyright © 1985 by the American Society of Animal Science.