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Kansas State University, Manhattan 66506
Abstract
An experiment using 40 Angus or Brahman x Angus preconditioned feeder calves was conducted to evaluate the influence of shipping on cellular immune reactivity. Steers were allotted on the basis of weight and breed to a control or shipped group. Shipped steers were trucked 700 km to a feedlot; control steers remained at the ranch of origin. Total and differential leukocyte counts, phytohemagglutinin skin-test responses, lymphocyte blastogenic responses, monocyte phagocytic function, packed cell volumes and concentrations of plasma cortisol were determined before, immediately after and 1 wk after shipment. At unloading, total leukocytes were increased (P<.05) in shipped Angus steers. Shipped steers also had higher (P<.01) numbers of neutrophils. Skin-test responses to phytohemagglutinin were higher (P<.05) in Angus than in Brahman x Angus steers, but shipping did not influence the reaction. Lymphocyte blastogenic responses were lower (P<.05) in shipped steers; however, cortisol levels in plasma were not elevated (P>.10) in shipped calves. Monocyte phagocytosis and packed cell volume were not influenced by shipping. These data suggest that shipped steers have suppressed lymphocyte blastogenic responses.
1 Contribution 83-182-J, Kansas Agr. Exp. Sta.
2 Supported in part by formula funds provided by the U.S. Dept. of Agr. under Section 1433 of Public Law 95-113, Project 0339.
3 Dept. of Anat. and Physiol., College of Veterinary Medicine.
4 Dept. of Anim. Sci. and Ind., College of Agriculture.
5 We thank Danielle H. Topliff, Daniel Topliff, Karen Altenbernd, John McWhirter, Jose Rodriquez, Susan Dolezal, Karen TerHune and Wade Kuhlmann for their excellent technical assistance. Appreciation is also expressed to Jim Horne and Dwayne Fussell of the Kerr Foundation, Inc. for their cooperation in this study.
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