J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J. Anim Sci. 1983. 57:1270-1275.
© 1983 American Society of Animal Science
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Murray, F. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Murray, F. A.

Effects of Dichlorvos on Lymphocyte Reactivity during Pregnancy in the Pig1,2,3,

Finnie A. Murray

Ohio Agricultural Research and Development Center, Wooster 44691

Abstract

This experiment was performed utilizing a total of 21 primiparous crossbred sows to determine whether a state of immunological suppression occurs during the latter stages of pregnancy in the pig and whether dichlorvos treatment affects immunological function of sows. Immunological reactivity was monitored by the use of in vitro lymphocyte transformation experiments employing the mitogens phytohemagglutinin (PHA), concanavalin A (Con A), pokeweed mitogen (PWM) and lipopolysaccharide (LPS). The degree of blastogenesis of lymphocytes recovered from animals on this experiment was not affected by dichlorvos treatment. Blastogenesis was not affected by stage of pregnancy except in the case of that induced by LPS, which decreased (P<.05) with advancing pregnancy. Sera from animals in this experiment were tested in a PHA-induced lymphocyte transformation experiment and it was found that sera from control animals were not inhibitory at any time. On the other hand, sera from dichlorvos-treated sows inhibited (P<.01) PHA-induced blastogenesis. The possibility exists that dichlorvos may increase fetal survival by inhibiting the ability of the sow to immunologically damage the fetus.

Footnotes

1 Approved for publication as Journal Article No. 29-82 of the Ohio Agr. Res. and Develop. Center, Wooster 44691.

2 Dept. of Anim. Sci.

3 Supported by a grant from Shell Development Co., Modesto, CA. The technical assistance of J. W. Farrell, A. P. Grifo, Jr. and N. Roxas is greatly appreciated. The author also thanks Bev Fisher who typed the manuscript.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1983 by the American Society of Animal Science.