J. Anim Sci.
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J. Anim Sci. 1983. 57:638-644.
© 1983 American Society of Animal Science
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Effect of Parenteral Iron on Serum Electrolytes of the Baby Pig1

P. K. Ku2, E. R. Miller2,3 and D. E. Ullrey2

Michigan State University, East Lansing 48824

3 To whom reprint request should be sent.

Abstract

Twenty-eight 4-d-old nursing pigs were used in two trials to evaluate the effects of im injection of iron (Fe) from Fe-dextran upon subsequent serum mineral concentrations. An im injection of 150 mg of Fe from Fe-dextran was given to all pigs (n = 17) in trial 1. Serum Fe concentration increased rapidly from an initial mean of 65 to 3,466 µg/dl at 6 h postinjection (PI), 5,712 µg/dl at 24 h PI, then fell to 317 µg/dl at 4 d PI, 143 µg/dl at 7 d PI and remained about 100 µg/dl at 14, 21 and 28 d PI. Concentrations of other serum minerals did not appear to be influenced by the Fe-dextran injection. Treatments of pigs (n = 11) in trial 2 were no injection, injection of dextran only, injection of 100 mg Fe from Fe-dextran and injection of 200 mg Fe from Fe-dextran. Serum Fe concentration increased rapidly after Fe-dextran injection, rising to a peak of 11,028 µg/dl at 6 h PI from the 100-mg Fe injection arid 17,012 µg/dl at 6 h PI from the 200-mg Fe injection. Serum Fe concentration dropped steadily in pigs that were given no injection or injected with dextran only. Seven days after trial 2 started, all pigs that had received no injection or dextran only were injected with 100 mg Fe from Fe-dextran. At 14, 21 and 28 d of the trial their serum Fe concentration was similar to that of other pigs in the trial. Changes in concentration of serum Zn, Cu, Mg, Ca, Na, K and inorganic P were age related and not significantly influenced by Fe injections.

Footnotes

1 Michigan Agr. Exp. Sta. Journal Article 10567.

2 Dept. of Anim. Sci.






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