HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hagemeier, D. L. Articles by Wahlstrom, R. C. Search for Related Content PubMed PubMed Citation Articles by Hagemeier, D. L. Articles by Wahlstrom, R. C.

Effects of Excess Arginine on Swine Growth and Plasma Amino Acid Levels¹

South Dakota State University, Brookings 57007

Abstract

One hundred seventy-six crossbred weaned pigs (4 to 5 wk old) were used in two growth trials to determine the effect of excess arginine on pig growth and plasma amino acid levels. In the first 28-d growth trial, two lysine levels (1.03 and 1.26%) and three arginine levels (.94, 1.29 and 1.63%) were used in a nested treatment arrangement. Lysine supplementation improved daily gains (P<.05), tended to improve feed efficiency (P<.12) and caused a general reduction in plasma essential amino acid levels. Arginine had no effect on daily gain or feed intake, but pigs fed 1.03% lysine and 1.63% arginine had reduced gain/feed (P<.05). Arginine did not affect gain/feed of pigs fed 1.26% lysine. Plasma lysine levels were reduced (P<.06) by excess arginine in pigs fed 1.26% lysine, but not in pigs fed 1.03% lysine. The four treatments for the second 26-d growth trial consisted of three diets containing .92% lysine and either .72, 1.10 or 1.61% arginine and a positive lysine control (1.10% lysine, .72% arginine). Lysine was the limiting amino acid in the basal diet, but arginine had no effect on daily gain, daily feed intake, gain/feed or plasma lysine levels. Plasma threonine and methionine levels were reduced by excess arginine in both experiments, while the other plasma essential amino acid levels were not affected by dietary arginine. Conclusions are that large excesses of added arginine may affect lysine utilization, but pig performance was affected only when excess arginine was combined with a lysine deficiency. The arginine levels similar to those found in grain-soybean meal swine diets had no effect on pig performance in these experiments.

¹ Published with the approval of the Director of the South Dakota Agr. Exp. Sta. as Pub. No. 1854 of the Journal Series.

² Present address: Kent Feeds, Inc., 1600 Oregon Street, Muscatine, IA 52761.

³ Dept. of Anim. and Range Sci.

This article has been cited by other articles:

				G. Wu, F. W. Bazer, T. A. Cudd, W. S. Jobgen, S. W. Kim, A. Lassala, P. Li, J. H. Matis, C. J. Meininger, and T. E. Spencer Pharmacokinetics and Safety of Arginine Supplementation in Animals J. Nutr., June 1, 2007; 137(6): 1673S - 1680S. [Abstract] [Full Text] [PDF]

				C. Nieves Jr, H. S. Sitren, K. A. Herrlinger-Garcia, and B. Langkamp-Henken Pharmacologic Levels of Dietary Arginine in CB6F1 Mice Increase Serum Ammonia in the Healthy State and Serum Nitrite in Endotoxemia JPEN J Parenter Enteral Nutr, March 1, 2007; 31(2): 101 - 108. [Abstract] [Full Text] [PDF]

				M. S. Awawdeh, E. C. Titgemeyer, G. F. Schroeder, and D. P. Gnad Excess amino acid supply improves methionine and leucine utilization by growing steers J Anim Sci, July 1, 2006; 84(7): 1801 - 1810. [Abstract] [Full Text] [PDF]