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Effects of Lasalocid or Monensin on Legume or Grain (FeedLot) Bloat^1,2,3,4,

Kansas State University, Manhattan 66506

Abstract

Doses of .66 to .99 mg monensin/kg body weight reduced legume bloat in cattle about 66% when compared with pretreatment bloat scores. Similar doses of lasalocid reduced legume bloat about 26%. A dose of 44 mg poloxalene/kg body weight (recommended dose for field use) reduced legume bloat 100%. Monensin or lasalocid combined with 25 or 50% of the recommended dose of poloxalene reduced bloat under that of the antibiotics alone, but did not achieve 100% reduction. The antibiotic thiopeptin provided no preventive effect on legume bloat. Lasalocid, monensin or an experimental polyether antibiotic (x-14,547 A) at a dose of 1.32 mg/kg body weight when tested on cattle bloated on high grain diets reduced bloat by 92, 64 and 25%, respectively. Lasalocid at .66 mg/kg effectively prevented bloat from developing when given to animals before the feeding of high grain diets; however, a 1.32-mg dose was required to control bloat in cattle that were already bloating before they were given lasalocid. A dose of 1.32 mg salin-omycin was ineffective in controlling grain bloat.

¹ Contribution 82-244-j, Ruminant Nutr. Group, Dept. of Anim. Sci. and Ind., Dept. of Statistics and Div. of Biol., Kansas Agr. Exp. Sta.

² Supported in part by grants from Hoffman Laroche, Inc., Nutley, NJ and Smith Kline Animal Health Products, Philadelphia, PA.

³ The assistance of Lloyd Manthe and Artie Dayton with the cattle is appreciated.

⁴ Authors are grateful to Fujisawa Co., Tokyo, Japan for furnishing the thiopeptin.

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