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The Pennsylvania State University, University Park 16802
2 Nutrition Program, College of Human Development. Author to whom all correspondence should be addressed.
Abstract
The biological mechanisms that regulate the synthesis and degradation of lipids and lipid transport in plasma are of great significance to animal agriculture. Regulation of lipid synthesis and degradation in meat animals has been studied to some extent. However, the role of plasma lipoproteins in transporting lipid to extrahepatic tissues in meat animals is not well defined. In addition, the knowledge that certain constituents of plasma lipoproteins influence pathways of triglyceride and cholesterol metabolism in adipose tissue, liver and skeletal muscle of humans and rodents has not been widely applied by animal scientists studying the mechanisms that regulate adipose tissue growth in meat animals. Therefore, this review will discuss lipoprotein metabolism and the mechanisms by which constituents of lipoproteins influence lipid metabolism in humans and rodents with application to meat animals.
1 The authors wish to thank David Mela and Drs. Michael Green and Robert McCarthy for their critical review and helpful comments. The superb efforts of Mrs. Shelby Hoy and Donna Lance in typing this review are gready appreciated. Authorized for publication as paper no. 6226 in the journal series of the Pennsylvania Agr. Exp. Sta.
3 Dept. of Dairy and Anim. Sci., College of Agriculture.
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