J. Anim Sci.
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J. Anim Sci. 1982. 54:1012-1016.
© 1982 American Society of Animal Science

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Estrogens and Piglet Viability. I. Serum Estrogen Concentrations in Piglets1

L. A. Bate and R. R. Hacker2

University of Guelph,3, Guelph. Ontario N1G 2W1

Abstract

An experiment was conducted to establish estrogen (Es) levels in piglet serum up to 13 h after birth. Treated piglets were given an injection of estradiol benzoate into the vena cava immediately after birth. Control piglets were similarly injected with saline solution. Blood samples were obtained frequently for monitoring Es levels. Each sample was analyzed for estrone (E1), estrone sulphate (E1SO4) and estradiol-17β (E2) by radioimmunoassay. Immediately after birth, Es declined at a very fast rate for 4 h and thereafter declined slowly until 9 h, when a small recovery occurred. There were no differences (P>.05) in the initial concentrations of Es between the control and treated groups. Injected estradiol benzoate did not significantly increase serum Es concentration (P>.05) by 5 min postinjection in treated animals, but sustained a trend showing higher levels of Es than the control until 4 h. At birth, E1SO4 was the Es with the highest concentration in piglet serum, followed by E1 and E2. The sharpest decline after birth occurred in E1SO4, which fell to lower values than E1 by 3 h. We conclude that an undetermined catabolic system for Es allows the piglet to eliminate or transform Es to other compounds.


Footnotes

1 This study was supported by Agriculture Canada, the Ontario Pork Producers Marketing Board and the Ontario Ministry of Agriculture and Food

2 The authors wish to thank J. Hoover, for her contribution in data collection and laboratory analysis and A. Lun, for RIA preparation

3 Dept. of Anim. and Poul. Sci.







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