HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Meyer, W. R. Articles by Moxon, A. L. Search for Related Content PubMed Articles by Meyer, W. R. Articles by Moxon, A. L.

Value of Dietary Selenium and Vitamin E for Weanling Swine as Measured by Performance and Tissue Selenium and Glutathione Peroxidase Activities^1,2,

The Ohio Agricultural Research and Development Center, Wooster 44691 and and The Ohio State University, Columbus 43210

Abstract

Three replicates of a 3 x 5 factorial experiment (randomized complete block) were conducted with 360 4-week-old weanling pigs to assess the value of feeding supplemental vitamin E and inorganic Se during a 5-week postweaning period. Pigs were fed 20% protein corn-soybean meal diets containing 0, 10 or 20 IU vitamin E/kg and(or) .1, .3, .5, 1.0 or 2.0 ppm supplemental Se as sodium selenite. At the end of the postweaning trial, 10 pigs from each of the four lower Se treatment groups were fed .1 ppm Se and 10 IU vitamin E/kg to 100 kg body weight for determination of tissue Se carry-over. Pig performance results to 35 days postweaning were similar at all vitamin E and Se levels. Plasma Se initially decreased by 7 days postweaning when .1 ppm Se was provided, but increased when the higher levels were fed. During ensuing weeks, plasma Se increased cubically with increasing levels of dietary Se. Plasma tocopherol decreased within 7 days postweaning in all treatment groups. Supplementation with 10 or 20 IU vitamin E increased plasma tocopherol as the experiment progressed, but no pig group attained the level measured at weaning. Se tissue concentrations increased and plateaued as dietary Se increased, with the liver appearing to be the major storage tissue. Plasma and liver Se concentrations appeared to parallel one another as dietary Se increased. Vitamin E supplementation resulted in lower tissue Se concentrations. Weekly plasma and liver glutathione peroxidase (GSH-Px) activity increased and plateaued with increasing levels of dietary Se. The dietary Se requirement progressively decreased with time postweaning. Breakpoint regression GSH-Px analyses of both plasma and liver estimated the requirement at .35 ppm Se (total concentration) 35 days postweaning. Total or Se-dependent liver GSH-Px increased in a parallel manner to dietary Se levels after 35 days postweaning, while Se-independent GSH-Px was constant. No residual carry-over of tissue Se was evident at 100 kg body weight in any of the postweaning groups.

¹ Approved for publication as Journal Article 96-80 of the Ohio Agr. Res. and Devel. Center, Wooster.

² Appreciation is expressed to J. Reed, T. Hartman, A. Lane and D. Hickman for their help in the collection of data and samples and to Dr. J. Holman for the statistical analysis.

³ Dept of Anim. Sci., Ohio Agr. Res. and Devel. Center, Wooster.

This article has been cited by other articles:

				J. E. Oldfield Some recollections of early swine research with selenium and vitamin E J Anim Sci, February 1, 2003; 81(14_suppl_2): E145 - 148. [Abstract] [Full Text] [PDF]

				S. Ching, D. C. Mahan, T. G. Wiseman, and N. D. Fastinger Evaluating the antioxidant status of weanling pigs fed dietary vitamins A and E J Anim Sci, September 1, 2002; 80(9): 2396 - 2401. [Abstract] [Full Text] [PDF]

				X. G. Lei, H. M. Dann, D. A. Ross, W.-H. Cheng,, G. F. Combs Jr., and K. R. Roneker Dietary Selenium Supplementation Is Required to Support Full Expression of Three Selenium-Dependent Glutathione Peroxidases in Various Tissues of Weanling Pigs J. Nutr., January 1, 1998; 128(1): 130 - 135. [Abstract] [Full Text]