J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J. Anim Sci. 1981. 52:75-82.
© 1981 American Society of Animal Science
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by DiMarco, N. M.
Right arrow Articles by Whitehurst, G. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by DiMarco, N. M.
Right arrow Articles by Whitehurst, G. B.

Effect of Fasting on Free Fatty Acid, Glycerol and Cholesterol Concentrations in Blood Plasma and Lipoprotein Lipase Activity in Adipose Tissue of Cattle1

Nancy M. DiMarco2, Donald C. Beitz and Garnett B. Whitehurst3

Iowa State University,4, Ames 50011

Abstract

Contributing factors in the regulation of triglyceride deposition in and fatty acid release from bovine adipose tissue were investigated. Six Holstein steers were fasted for 9 days and then refed for 41 days. Blood samples from the jugular vein and adipose tissue samples from backfat biopsies were taken during fasting and refeeding periods. Concentrations of plasma free fatty acids, glycerol and cholesterol and activity of lipoprotein lipase in adipose tissue from fasted and refed steers were measured. Plasma free fatty acid concentration increased almost eightfold during fasting. After 4 days of refeeding, free fatty acids in plasma had returned to basal concentration. Fasting had no effect on plasma cholesterol concentration; during refeeding, concentration decreased slightly and then returned to the basal concentration. Lipoprotein lipase activity decreased to 37% of the basal concentration during fasting and increased to 100% above prefasting values during refeeding. Significant changes in plasma free fatty acid and glycerol concentrations and in activity of lipoprotein lipase in adipose tissue during fasting and refeeding suggest that fatty acid mobilization and triglyceride uptake by adipose tissue of cattle adapt to great changes in energy intake. Correlations of measured blood metabolites in fasted and refed steers demonstrate that changes in rates of lipolysis and of triglyceride uptake by adipose tissue vary in a reciprocal manner.

Footnotes

1 Journal Paper No. J-9688 of the Iowa Agr. and Home Econ. Exp. Sta., Ames. Project No. 2187. A paper on part of this study was presented at the Annu. Meet, of the American Institute of Nutrition, Atlantic City, NJ, April 1978. Fed. Proc. 37:411 (Abstr.).

2 Present address: Dept of Physiol. Chem., Ohio State Univ., Columbus 43210.

3 Present address: Dept of Pathol., Univ. of Alabama Medical Center, Birmingham 35294.

4 Nutritional Physiology Group, Dept. of Anim. Sci., Iowa State Univ., Ames 50011. The authors acknowledge the assistance of Paul Fullerton in performing analytical analyses.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by the American Society of Animal Science.