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Tiamulin in the Feed for the Prevention of Swine Dysentery and Growth Promotion of Growing Pigs

Squibb Agricultural Research Center, E. R. Squibb & Sons, Inc., Three Bridges, NJ 08887

Abstract

Tiamulin, a semisynthetic antibiotic, was fed to growing pigs to determine its value in the prevention of swine dysentery due to Treponema hyodysenteriae and to determine its value on weight gain and feed conversion of growing pigs.

Three experiments involving 100 growing pigs were used to test the effect of tiamulin at .0022% to .0044% (20 to 40 g/907 kg) on pigs infected with T. hyodysenteriae. When fed at .0022% tiamulin was not adequate in preventing the disease, but levels of .00275%, .0033%, .00385% and .0044% were effective in preventing the development of the disease.

Two experiments with 299 pigs were conducted to determine the effect of tiamulin fed at .0022%, .003 3% and .0055% and tiamulin (.0022% and .0055%) plus .011% sulfamethazine on growth and feed efficiency of normal uninfected growing pigs. Tiamulin fed at .0033% and .0055% significantly improved growth (P<.05 and P<.10, respectively). Tiamulin fed at .0022% and .0055% plus .011% sulfamethazine also improved growth (P<.05 and P<.01, respectively). Tiamulin at .0055% plus sulfamethazine improved feed efficiency (P<.05) after 6 weeks on test. There were no other differences due to treatments.