J. Anim Sci.
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J. Anim Sci. 1979. 49:128-133.
© 1979 American Society of Animal Science
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Influence of a Sub-Therapeutic Level of Virginiamycin in Feed on the Incidence and Persistence of Salmonella typhimurium in Experimentally Infected Swine1

Mamdouh H. Abou-Youssef2, C. John DiCuollo, Cecil R. Miller and George C. Scott

Applebrook Research Center, SmithKline Animal Health Products, West Chester, PA 19380

Abstract

Swine were infected with Salmonella typhimurium, USDA #295, and treated with virginiamycin medicated feed continuously at a level of 55 g/metric ton for approximately 2 months. The incidence and persistence of shedding of this organism in the feces and in selected tissues were determined. No significant changes in the course of the infection were detected when virginiamycin treated animals were compared to nonmedicated infected controls.

Footnotes

1 The authors wish to thank Dr. Michael Free of SmithKline Corp. for the statistical analysis of the Salmonella data; Tana L. Joy of the Springborn Institute for Bioresearch Inc., for technical assistance.

2 Springborn Institute for Bioresearch Inc., Spencerville, OH 45887.






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Copyright © 1979 by the American Society of Animal Science.