J. Anim Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J. Anim Sci. 1978. 47:666-671.
© 1978 American Society of Animal Science
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Noden, P. A.
Right arrow Articles by Hafs, H. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Noden, P. A.
Right arrow Articles by Hafs, H. D.

Early Changes in Serum Progesterone, Estradiol and LH during Prostaglandin F2{alpha}-induced Luteolysis in Mares1

P. A. Noden2, W. D. Oxender2,3, and H. D. Hafs2

Michigan State University, East Lansing 48824

Abstract

Blood serum progesterone, estradiol and LH were quantified during luteolysis induced by prostaglandin F2{alpha} (PGF2{alpha}) in eight mares, and during a comparable time period in six control mares. In control mares progesterone averaged 9.2 ± 1.5 ng/ml when saline was injected and did not change more than 1.1 ng/ml on the average for the next 48 hours. However after PGF2{alpha}, progesterone decreased from 7.7 ± 1.1 ng/ml to .6 ± .1 ng/ml in 48 hours. The mares began estrus at 3.8 days on the average after PGF2{alpha}. Luteolysis was accompanied by a transient increase in serum radioimmunoreactive progestogens; progestogens increased (P<.05) from 7.7 ± 1.1 to 10.3 ± 1.3 ng/ml at 10 min, then decreased (P<.05) to 4.8 ± .5 at 1 hr, 1.2 ± .4 at 24 hours. Meanwhile estradiol increased (P<.05) nearly twofold from 4.9 ± 1.1 to 8.0 ± 1.5 pg/ml at 1 hr after PGF2{alpha} treatment then decreased to less than 4.0 pg/ml at 8 hr and increased to 7.2 ± 2.0 pg/ml at 96 hours. Serum LH increased (P<.05) over two fold from 102 ± 24 to 237 ± 72 ng/ml at 30 min after PGF2{alpha}; LH then decreased (P<.01) to 95 ± 26 ng/ml at 8 hours. In the six mares treated with saline LH was more variable (P<.05) than after PGF2{alpha} but no consistent changes were observed. In conclusion transient changes in serum progestogens, LH and estradiol precede the decline in progesterone which follows PGF2{alpha} treatment in mares.

Footnotes

1 Published with the approval of the Director of the Agricultural Experiment Station as Paper No. 8372. This research was supported in part by the American Quarter Horse Association and USPHS Research Grant HD 06948.

2 Department of Dairy Science.

3 Department of Large Animal Surgery and Medicine.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1978 by the American Society of Animal Science.