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Lactic Acidosis: a Factor Associated with Equine Laminitis^{1 ,2,}

University of Missouri, Columbia 65201

Abstract

Plasma L-lactate was measured in 31 horses subsequent to carbohydrate overload of the gastrointestinal tract. The greatest increase in lactate was observed in horses dying of circulatory collapse; horses developing laminitis had a lesser increase, while horses with neither syndrome had only a slight increase. In retrospect, either death associated with complete circulatory collapse or laminitis associated with survival could have been predicted 16 to 24 hr after carbohydrate overload. Only two of five horses that died of cardiovascular collapse exhibited signs of lameness prior to death.

¹ From the department of Veterinary Medicine and Surgery, School of Veterinary Medicine and Dalton Research Center (Garner, Coffman and Hahn), and the Department of Animal Science, College of Agriculture and Sinclair Research Farm (Hutcheson), University of Missouri, Columbia 65201.

² Supported in part by the American Quarter Horse Association and Veterinary Research Council Grant #623.

³ The authors extend their appreciation to Dan Hatfield, Tom Butera and Don Ryker for their diligent technical support of this investigation.

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