HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Wettemann, R. P. Articles by Turman, E. J. Search for Related Content PubMed PubMed Citation Articles by Wettemann, R. P. Articles by Turman, E. J.

Influence of Prostaglandin F₂ on Endocrine Changes at Parturition in Gilts¹, ^,2

Oklahoma Agricultural Experiment Station, Stillwater 74074

Abstract

Twelve 13-month-old crossbred pregnant gilts were used to determine the effects of prostaglandin F₂(PGF₂) on the length of gestation and endocrine changes at parturition. At day 105 of gestation, gilts were anesthetized and indwelling cannulae were placed into the anterior venae cavae. Gilts were injected intramuscularly with either 10 mg PGF₂ or saline on day 108 of gestation, with parturition subsequently occurring at 33 ± 2 hr and 105 ± 15 hr (P<.005), respectively. Plasma progesterone concentrations were similar in PGF₂ and control gilts prior to treatment and at 4 hr after treatment, but progesterone was reduced during 8 to 24 hr after PGF_2a treatment (P<005). Total plasma corticoids were increased after PGF₂ treatment (P<005) but estrone and estradiol concentrations were not significantly altered (P>.10). At parturition plasma concentrations of progesterone, estrone, corticoids and LH were similar in PGF_2a and control gilts but estradiol concentrations were less in the treated gilts (P<10). It was concluded that PGF₂ given on day 108 of pregnancy will induce synchronized parturition in gilts.

¹ Journal Article 3140 of the Agricultural Experiment Station, Oklahoma State University, Stillwater.

² We thank Dr. James Lauderdale (Upjohn Company) for his advice and for supplying the prostaglandin F₂ -Tham salt. We also thank Dr. G. D. Niswender (Colorado State University) for the progesterone-6ß-BSA and porcine LH antersera; Dr. S. A. Tillson (Alza Research) for the supply of antiserum to the conjugate l,3,5(10)-estratriene-3, 17ß-diol, 17ß-succinyl-BSA; Dr. L. E. Reichert, Jr. (Emory University) for the supply of porcine LH for iodination, and the NIAMD for the supply of LH standard (NIH-LH-S^{1 8}).

³ Department of Animal Sciences and Industry, Oklahoma State University, Stillwater 74074.

⁴ Present address: Department of Animal, Range and Wildlife Sciences, Las Graces, New Mexico 88001.

⁵ Present address: Department of Animal Science, University of Arkansas, Fayetteville 72701.