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Cornell University, Ithaca, New York 14853,5
Abstract
Changes in body weight, serum protein and albumin were followed during defined periods of protein-calorie malnutrition in the pig. Pregnant pigs fed protein restricted diets gained less weight (P<.05) during gestation and their respective fetuses weighed less compared to the controls (P<.05). There was growth retardation in the progeny of dams severely protein malnourished during gestation (P<.05). Restricting protein intake during postnatal life resulted in growth retardation (P<.05) during the depletion period. Serum protein and albumin were reduced in protein deprived pregnant pigs and their fetuses (P<.05) but no significant differences were observed in serum protein levels in the progeny of malnourished dams postnatally compared to the control group. Protein deficiency, but not energy restriction, from 3 to 11 weeks of age led to reduced serum protein and albumin levels during the depletion period.
1 Present address: Applied Nutrition Unit, University of Ibadan, Nigeria.
2 Present address: Departmento de Fisiologia, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo, Brasil.
3 Department of Animal Science.
4 Division of Nutritional Sciences.
5 The authors gratefully acknowledge David Kirtland, Allan Chandler and Chuck Avery for care and feeding of the experimental animals, Priscilla Lawrence for stenographic work and R. G. Eggert, American Cyanamid Co., Princeton, N. J. for providing the antibiotic feed supplements. The data are from the Ph.D. thesis of the senior author. Supported in part by funds provided through the State University of New York and Public Health Research Grant no. HD-02581 from the National Institute of Child Healthand Human Development.
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