J. Anim Sci.
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J. Anim Sci. 1976. 42:381-392.
© 1976 American Society of Animal Science

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Late Gestation Feeding of Dichlorvos: A Physiological Characterization of the Neonate and a Growth-Survival Response

David G. Siers, David E. DeKay, Harry J. Mersmann, Lloyd J. Brown and Hubert C. Stanton1

Shell Development Company,2, Modesto, California 95352

Abstract

One-hundred lightly parasitized crossbred sows were randomly divided into two groups on gestation day 80. Each treated sow received 1,000 mg dichlorvos as an ATGARD® C top dress on her daily feed allowance (2.7 kg) from day 80 until farrowing. The control sows received the same daily feed allowance and all sows were individually fed from gestation day 80 until farrowing. All farrowings were attended and the following data were collected for every litter at birth: individual pig weights, viability score for each pig, number of live and dead pigs per litter, time interval between pigs, umbilical blood glucose and lactate for each pig.

One-half of the treated and control litters were reared to market weight (91 kg). The individual pig weights and the number alive per litter were recorded for these litters at 7, 14, 21, 60, 120 and 160 days of age.

The remaining half of the control and treated litters were used to study the possible interaction of the dichlorvos treatment and a temperature stress on the neonate.Each remaining litter (control and treated) was randomly split into two equal sized groups each containing the same proportion of the two sexes (when possible). One group was placed at 5 C for 1 hr, while the other remained at 34 C for 1 hour. After 1 hr, both gr0ups were sacrificed.

The dichlorvos treatment increased the number of ]iveborn pigs per litter. At 7, 14, 21, 60, 120 and 160 days the dichlorvos treatment resulted in litters that were heavier. The lipid content of the colostrum from treated sows was higher than from control sows. The temperature stress influenced nearly all of the physiological measurements made on the blood and tissues of the neonates. The dichlorvos influenced the CPK level, the beta globulin level and possibl.), the gamma globulin level of the sacrificed neonates.


Footnotes

1 The authors wish to acknowledge the exceptional sacrifice and technical input of the following persons: M. C. Arakelian, C. Bailey, J. M. Houk, R. L. Mueller, J. Phinney, M. C. Underwood, R. A. Presant, V. A. Molina, D. K. Harrington, G. M. Handschumacher, and G. B. Durnbaugh and the cooperation of D. H. Hardage and W. M. Creek.

2 Biological Sciences Research Center.







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Copyright © 1976 by the American Society of Animal Science.